Splenomegaly is one of the common complications of malaria most commonly associated with Plasmodium Vivax. Due to inadequate treatment, spleen can harbor parasite, which causes recurrent infection leading to splenomegaly and splenic rupture. Spleen is more prone to rupture in acute phase of infection. The exact mechanism of splenic rupture is still unknown but trauma, pressure of abdominal muscles on spleen due to sneezing and coughing plays important rule. Spontaneous splenic rupture although very rare in normal sized spleen, as in case presented here, is life-threatening complication. Therefore, early diagnosis and management plays important role in saving life.

Objective: To compare the efficacy lignocaine alone with lignocaine plus ketorolac in intravenous regionalanesthesia technique in terms of mean pain and time for analgesia.Study Design: Randomized controlled trial.Place and Duration of Study: The study was carried out at Department of Anesthesia, KRL Hospital, Islamabadfrom April 2017 to October 2017.Materials and Methods: Sixty consecutive patients undergoing ambulatory hand/forearm surgery, whofulfilled inclusion criteria. They were divided into two equal groups of 30 patients in each. In “Group A”Lignocaine only and in “Group B” Lignocaine plus ketorolac was used for intravenous regional anesthesia(IVRA).Results: Pain relief was better in Group B as shown by comparison of pain in Group A at 10, 20, 30, 40 and 60minutes was as 0.13+0.35 v/s 0.27+0.52, p value was 0.24, 0.23+0.43 v/s 1.60+0.50, p value was 0.000,1.27+0.45 v/s 1.53+0.51, p value was 0.03, 1.23+0.43 v/s 2.67+0.48, p value was 0.0001 and 1.27+0.45 v/s3.53+0.68, p value was 0.0001 respectively.Conclusion: Lignocaine plus ketorolac in intravenous regional anesthesia technique was significantly betterwhen compared with lignocaine alone in terms of mean pain and time for analgesia.How to cite this: Ghori K, Ahmad MS, Sufyan A, Maka TA. Lignocaine Alone Vs Lignocaine plus Ketorolac in Reducing Perioperative Pain in Intravenous Regional Anesthesia. Life and Science. 2022; 3(3): 105-109. doi: http://doi.org/10.37185/LnS.1.1.204