Malignant schwannomas of the paranasal sinuses are extremely uncommon tumors, as only 18 well-documented cases have been previously published in the Englishlanguage literature. We report two new cases ofsolitary malignant schwannoma-one in a 23-year-old man and the other in a 45-year-old woman. Neither was associated with von Recklinghausen's disease. These tumors involved the maxillary sinus, nasal cavity, and orbit and extended intracranially. Following surgery, both patients experienced recurrences. The male patient developed a slowly enlarging intranasal mass at the same site 8 years following excision of the original tumor and postoperative radiotherapy. Microscopic examination ofthe recurrent tumor revealed that its features were similar histologically to those of the original. The female patient experienced a recurrence 1 year following her first operation.
We highlight the features of GH in the distal GIT - the 'outlet patch'. Association with PGA, surface dysplasia and adenocarcinoma suggests that lower tract GH can undergo neoplastic transformation.
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