No abstract

Multiple Instance Learning (MIL) gains popularity in many real-life machine learning applications due to its weakly supervised nature. However, the corresponding effort on explaining MIL lags behind, and it is usually limited to presenting instances of a bag that are crucial for a particular prediction. In this paper, we fill this gap by introducing ProtoMIL, a novel self-explainable MIL method inspired by the case-based reasoning process that operates on visual prototypes. Thanks to incorporating prototypical features into objects description, ProtoMIL unprecedentedly joins the model accuracy and fine-grained interpretability, which we present with the experiments on five recognized MIL datasets.

The rapid development of histopathology scanners allowed the digital transformation of pathology. Current devices fastly and accurately digitize histology slides on many magnifications, resulting in whole slide images (WSI). However, direct application of supervised deep learning methods to WSI highest magnification is impossible due to hardware limitations. That is why WSI classification is usually analyzed using standard Multiple Instance Learning (MIL) approaches, that do not explain their predictions, which is crucial for medical applications. In this work, we fill this gap by introducing ProtoMIL, a novel self-explainable MIL method inspired by the case-based reasoning process that operates on visual prototypes. Thanks to incorporating prototypical features into objects description, ProtoMIL unprecedentedly joins the model accuracy and fine-grained interpretability, as confirmed by the experiments conducted on five recognized whole-slide image datasets.

Active visual exploration addresses the issue of limited sensor capabilities in real-world scenarios, where successive observations are actively chosen based on the environment. To tackle this problem, we introduce a new technique called Attention-Map Entropy (AME). It leverages the internal uncertainty of the transformer-based model to determine the most informative observations. In contrast to existing solutions, it does not require additional loss components, which simplifies the training. Through experiments, which also mimic retina-like sensors, we show that such simplified training significantly improves the performance of reconstruction, segmentation and classification on publicly available datasets.