BACKGROUND The pathological spectrum of thyroid dysfunction varies from overactive to underactive thyroidism. It is a common Endocrine disorder worldwide and leads to major consequences in the absence of appropriate treatment. MATERIALS AND METHODS This is a hospital based retrospective study based on medical records from the period of January 2013 to December 2015. Thyroid hormones were evaluated by RIA for T3 & T4 and IRMA for TSH, kits supplied by BRIT, Mumbai. RESULTS 2322 study subjects comprised of males 403 and 1919 females. Thyroid dysfunction categorized was as hypothyroidism, subclinical hypothyroidism, hyperthyroidism and Subclinical hyperthyroidism as per reference values for thyroid hormones. Prevalence of thyroid dysfunction was 43.7% in females and females were more affected than males. Hypothyroidism 15.80% and Subclinical hypothyroidism 21.40% were higher than hyperthyroidism 3.91% and subclinical hyperthyroidism 2.58% subjects aged 30-45 years had a higher prevalence. Euthyroid subjects constituted 56.28%. CONCLUSION Study revealed high prevalence of abnormal thyroid function. Females and elderly are more susceptible. Since untreated thyroid disease leads to significant morbidity, public awareness in the context of primary care setting will be valuable.