The effectiveness of cash flows and liquidity contributions to the financial performance of deposit money banks in Nigeria have been of concern that requires special attention. Therefore, this study examined the "significance of Statement of Cash Flows (IAS 7) to the financial performance of listed deposit money banks in Nigeria". Ex-post facto research design was adopted. The population of the study was 14 while the sample of eleven banks was purposively selected mainly on available data from Nigeria Stock Exchange in 2019. Secondary data collection method was used in extracting data for periods between 2015 and 2019 from their published annual accounts. Both descriptive and inferential statistical methods were adopted using "correlation and regression analysis techniques". The findings of the study reveal that cash flow activities have no "significant effect on deposit money banks financial performance". However, when the moderating variable of banks' size was introduced, the result shows that Cash flows with moderating variable have a "significant effect on financial performance of deposit money banks in Nigeria". Also, the study established that there is no uniform method adopted by the listed banks in the preparation of the statement of cash flow analysis. The study recommended that the users of the statement should recognize the effect of banks' size before making any investment decision based on cash flow information. Regulators should persuade banks to adopt a uniform method of preparing Cash Flows Statement for easy comparison and analysis. Finally, contents and accuracy of Statement of Cash Flows should be of interest to both the regulators and external auditors because some stakeholders placed more reliance on the statements in making investment decisions.