Introduction the study assessed the prevalence and factors associated with psychiatric morbidity (an array of psychological disorders), and comorbid anxiety and depression among medical students in Ekiti State, Nigeria. Methods a cross-sectional study of medical students in two universities (one public and one private) in Ekiti state was conducted. A semi-structured questionnaire with adapted questions from the General Health Questionnaire and Hospital Anxiety and Depression Scale was used to obtain information on socio-demographic characteristics, psychiatric morbidity and comorbid anxiety and depression. Data was collected from April 2019 to August 2019. Data was analyzed using Statistical Package for Social Sciences (SPSS) version 21. Results a total of 944 medical students participated in the survey. The overall prevalence of psychiatric morbidity and comorbid anxiety and depression among the respondents was 25.0% (CI = 22.1-27.8) and 14.3% (CI = 12.3-16.5) respectively. The factors independently associated with psychiatric morbidity included being a student of a private institution [adjusted odds ratio [AOR] =6.533, [95% confidence interval [C.I] =3.298-12.940], average academic performance [AOR =1.711, [95% C.I =1.173-2.496], below average academic performance [AOR =2.425, [95% C.I =1.313-4.478], and having a father or a mother with highest level of formal education below first degree [AOR =3.147, [95% C.I =1.579-6.272] and [AOR =2.053, [95% C.I =1.074-3.927] respectively. The factors independently associated with comorbid anxiety and depression were being a student receiving less than one dollar equivalent per day as allowance [AOR = 1.953, [95% C.I = 1.135-3.360] and being a student from the Igbo ethnic group [AOR = 0.533, [95% C.I = 0.333-0.853]. Conclusion the prevalence of psychiatry morbidity and comorbid anxiety and depression was high among medical students in Ekiti State, Nigeria. Periodic medical [mental health] screening for medical students may be appropriate to screen, detect and manage psychiatric comorbidities. This will help to ensure optimal mental health for this group of university students.

Background: Essential workers are imperative in the fight against the coronavirus disease (COVID-19) pandemic.Aim: To assess the prevalence and factors associated with anxiety and depression among essential workers during the COVID-19 pandemic and lockdown.Setting: This study was set in Ekiti State, Nigeria.Method: This was a cross-sectional study involving essential workers in Ekiti State Nigeria, during the COVID-19 pandemic and lockdown. A total of 588 essential workers were sampled. Online socio-demographic variables and the Hospital Anxiety and Depression Scale, a 14 item self-reported questionnaire were used.Results: The prevalence of anxiety and depression among the respondents was 93.4% (CI = 91.2–95.2) and 64.3% (CI = 60.4–68.4) respectively. Among the health workers, the prevalence of anxiety and depression were 96.5% (CI =94.8–98.1) and 66.5% (CI = 60.5–69.8) respectively while the prevalence of anxiety and depressive symptoms among non- health workers were 84.6% (CI = 78.7–90.1) and 61.5% (CI = 54.2–69.4) respectively. The odds ratio (OR) of depressive symptoms was increased among, respondents who were not satisfied with the support they received from the government during the pandemic (AOR = 2.071, CI = 1.350–2.213), respondents that were 35 years and younger (AOR = 1.512, CI = 1.033–2.213) and reduced amongst Christians (AOR = 0.501, CI = 0.286–0.879). The odd of anxiety was increased among health workers compared to non-health workers (AOR = 3.700, CI = 1.744–7.851) and the odds of anxiety was reduced among respondents with previous history of mental illness (AOR = 0.215, CI = 0.049–0.943).Conclusion: Anxiety and depressive symptoms were common mental illness among essential workers working during the COVID-19 lockdown, therefore their mental health should be adequately considered to sustain the fight against the virus.

Objective: Adolescence is a transition period where drug experimentation is common. Spirituality and religiosity have been recognized by literature as having a possible role in stabilizing good physical and mental health. To compare the religiosity and spirituality among adolescents abusing a psychoactive substance and those not abusing psychoactive substances in a Nigerian hospital Methods: This was a cross-sectional descriptive study conducted among adolescent patients admitted to the drug rehabilitation unit and adolescents attending the General Outpatient Department of the ABUAD Multisystem Hospital, Ado-Ekiti. The Daily Spiritual Experience Scale and Centrality of Religiosity Scale were used Results: The prevalence of high religiosity and spirituality among the respondents was 57.9% and 56.1%. The prevalence of high religiosity and spirituality among respondents not abusing psychoactive substances was 62.9% and 62.6% respectively, while the level of high spirituality and religiosity among respondents abusing psychoactive substances was 53.0% and 49.1% respectively. A significant proportion of the respondents who had a low level of religiosity (55.9%) abused psychoactive substances than respondents who do not abuse psychoactive substances (45.7%) (X2=7.694 p=0.006). Similarly, more proportion of respondents who had a low level of spirituality (57.4%) abused psychoactive substances than respondents who do not abuse psychoactive substances (44.2%). The observation is statistically significant (X2=11.1, p<0.001). In addition, there was a significant positive correlation between the spirituality and religiosity scores among the respondents (r =0.50, p<0.001)  Conclusion: Psychoactive drug use among the respondent was associated with both low religiosity and spirituality. Therefore, religious activities should be encouraged among adolescents.

Background Coagulase-negative staphylococci (CoNS) are increasingly becoming emerging bacteria of ‘true’ clinical significance in hospital setting. We investigated an unusual rise in incidence of CoNS bacteraemia among in-patients in a private tertiary hospital, Southwest Nigeria and described ways of mitigation. Methods A descriptive epidemiology of all cases of CoNS bacteraemia reported among in-patients between April 2022 and June 2022 was conducted. Blood cultures were processed in an automated system. Phenotypic and molecular analyses of CoNS were done according to established guidelines. A multimodal infection prevention and control (IPC) approach by the World Health Organisation was implemented. Findings A total of 82 blood cultures (non-duplicate samples) were requested during the period. Of these, 30 (36.5%) were culture-positive and 10 of the isolates were CoNS (10/30, 33.3%). Cumulative incidence of CoNS bacteraemia was 12 cases per 100 patients over 90days from 1–2% in previous months. Staphylococcus haemolyticus (4/10, 40%), Staphylococcus hominis (3/10, 30%), Staphylococcus epidermidis (2/10, 20%) and Staphylococcus saccharolyticus (1/10, 10%) were identified. All isolates were resistant to ciprofloxacin, Trimethoprim-sulfamethoxazole and cefoxitin (methicillin-resistant) while they were all susceptible to both Vancomycin and linezolid. All the isolates fell into S. epidermidis and S. haemolyticus cluster groups. The rates reduced to baseline on the implementation of the IPC strategies. Conclusion The unusual rise of CoNS incidence in the hospital was caused by multi-drug resistant cluster groups of S. haemolyticus and S. epidermidis which was curtailed by the implementation of multimodal strategies.

Background: COVID-19 pandemic caused unexpected socio-economic changes globally. This study determined the prevalence and factors associated with perceived stress among essential workers during the COVID-19 lockdown in Ekiti State, Nigeria.Method: A cross-sectional descriptive study that involved 588 essential workers in Ekiti State, Nigeria during the COVID-19 lockdown. The Perceived Stress Scale was used in the study Chi-square test of statistical significance and multivariate analysis using binary logistic regression were used in the analysis and the level of statistical significance was determined by a p-value of <0.05.Results: The prevalence of high perceived stress levels among all the respondents, health workers, and non-health workers were 64.1% (63.3-70.6), while health workers and non-health workers had a prevalence of 70.1% (65.5 -73.3) and 56.5% (23.5-38.7) respectively. The majority of the respondents related their sources of stress to inadequate transportation (63.3%), hearing of COVID related news (47.4%), and lack of finance (55.1%). Using Logistic Regression respondent respondents who were not satisfied with the support they received from the government during the pandemic had three fold high stress levels than respondents who were satisfied with the support received from the government [AOR= 3.228, (CI= 1.771- 5.886)]. Furthermore, the odd of the high stress level was one fold increased among male respondents than female respondents [AOR = 1.08 CI= (1.410-6.215). Conclusion: Stress management is recommended given the high-stress level among essential workers.   French title: Niveau de stress perçu chez les travailleurs essentiels pendant le casanier du COVID-19 dans l'état d'Ekiti, au Nigéria Contexte général de l'étude : La pandémie de COVID-19 a provoqué des changements socio-économiques inattendus dans le monde. Cette étude a déterminé la prévalence et les facteurs liés au stress perçu à un niveau parmi les travailleurs essentiels pendant la période de confinement du COVID-19 dans l'état d'Ekiti, au Nigéria.Méthode de l'étude : Une étude descriptive transversale qui a impliqué 588 travailleurs essentiels dans l'état d'Ekiti, au Nigéria, dans le cadre du confinement COVID-19. L'échelle de stress perçu a été utilisée dans le test du Chi carré de l'étude et une analyse multi variée a été utilisée. Le niveau statistiquement significatif a été déterminé par une valeur p < 0,05.Résultats de l'étude: Le total des répondants non-agents de santé et agents de santé présentait une prévalence de niveaux élevés de stress perçu de 64,1% (63,3-70,6), 56,5% (23,5-38,7) et 70,1% (65,5 - 73,3). La majorité des répondants ont lié leurs sources de stress à un transport inadéquat (63,3 %), à l'audition de nouvelles liées à COVID (47,4 %) et au manque de financement (55,1 %) En utilisant la régression logistique, les répondants qui étaient insatisfaits du soutien gouvernemental pendant la pandémie avaient des niveaux de stress trois fois plus élevés que les répondants qui étaient insatisfaits du soutien gouvernemental [AOR= 3.228, (IC= 1.771-5.886)]. De plus, l'impair du niveau de stress élevé était un fois plus élevé chez les hommes interrogés que chez les femmes [AOR = 1,08 IC = (1,410-6,215).Conclusion : La gestion du stress est recommandée étant donné le niveau de stress élevé chez les travailleurs essentiels.