<p><em></em><em>Nerium oleander</em> is an evergreen flowering shrub or small tree distributed widely in the Mediterranean region. It is also a source of polyphenols and cardenolides ?? with insecticidal effect which could be a safe alternative of chemical control of insect pests. In the present work, five concentrations (0 %, 1 %, 2.5 %, 5 %, and 10 %) of ethanolic extract from <em>Nerium oleander </em>leaves<em> </em>were evaluated for its insecticidal effect against 3 to 4 days old <em>Myzus persicae </em>individuals under laboratory conditions. Obtained results showed a significant insecticidal effect with 70 % of mortality at the highest concentration (10 %). Total phenolic content of leaf ethanolic extract of this plant was 1721.36 mg gallic acid equivalent 100 g<sup>-1</sup> dry matter. The results obtained suggest that we could make bioinsecticides based on leaves ethanolic extracts from <em>N. oleander</em> which rich in polyphenols for use eventually in integrated pest management.</p>
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