COVID-19 is an infectious pandemic disease which is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Up to date, scientists are trying to identify a new specific antiviral drug to overcome this disease. Different methods are under study and evaluation in the entire world to control the virus, including blood plasma, blood purification, and antimicrobial and antiviral agents; however, there are no approved drugs yet. This review is focused on the conducted clinical trials worldwide, including the Iraq- Kurdistan region, China, USA, and Europe, to find relevant data on the agents with potential efficacy to treat the COVID-19 infection. The utmost commonly assessed therapies for this disease were chloroquine phosphate, hydroxyl-chloroquine, azithromycin, lopinavir/ritonavir, favipiravir, remdesivir, and alternatively, blood plasma, ivermectin in combination with doxycycline, and dexamethazone. This review suggests that blood plasma transfusion, the combination of hydroxyl-chloroquine with azithromycin, and remdesivir were the most abundant and efficient therapies. Thus, more light could be shed on these particular drugs on the road of drug investigation against COVID-19 pneumonia.

Two field experiments were performed to study the response of two species , Nigella sativa L. and Nigella arvensis L. within different sowing dates at spring and autumn seasons which included 1st and 20th March, 10th April and 1st May for spring season, while the sowing dates for the autumn season were, 2nd November, 21st November, 11th December, 31stDecember and 20thJanuary. Both experiments conducted according to the Completely Randomized Block Design (CRBD) within three replications at hallabja/Kurdistan Region, located [35°12'48.7"N; 45°57'34.4"E] and the altitude was 596 masl. Results showed that among the four different sowing dates of spring cultivations,  both species were responded to only 1st and 20th March date with some superiority of the 1st March, otherwise the survival and their yield were not acceptable at sowing date later than 20th March, while at the autumn cultivation, both species responded to all sowing date, but not to be later than 31st December, the early dates 2nd November and 21st November were showed significant differences in most yield traits. The result of the study showed that, due to the favorable environmental condition and the longer period of growth at autumn cultivation, most of the yield traits were gained significant values as the average of both species and different sowing dates of autumn compared to that occurred at spring cultivations. Some chemical contents of both species under the different environment conditions showed significant differences. Generally, N. sativa compared to N. arvensis contained more significant chemical compounds in the term of carbohydrates and protein at autumn, fixed and volatile oils at spring.

This study investigated the watercress (Nasturtium officinale) belongs to Brassicaceae grown at Reshen area where is located in Halabja -Iraqi Kurdistan Region, to investigate the effect of different sources of water in different collection times on the Phenotypic (morphological characters) and content of the chemical compounds of plants which studied which illustrate the comparative of minerals which exist in clear and polluted water and also exist in the vegetative and the root parts of collection of watercress (Nasturtium officinale), which are growing in this area. The results have shown; watercress obtained from clear water in both times are healthy more than polluted water. A large amount of nutrient variability were observed in measured traits, the measured traits showed significant variations across the two sources of water and plants collection time distribution and there were the significant difference in measured traits at two different sources of water chemically (i.e., Ca, N, and Fe).polluted water in two times (first and second times), caused increasing vegetative fresh weight and root, dry vegetative and root parts, branch number, plant height significantly. The result shows that plant from polluted water in second collection time had a better response than other treatments, but it's not healthy.Keywords: Brassicaceae, Clear and polluted water, Phenotypic, watercress, Halabja.