Introduction: Throughout the advancement of subsurface caries lesions, mineral is disbanded out of the enamel, causing enhanced penetrability that look like clinically as incipient or white spot lesions. Nowadays, these lesions are regularly treated by increasing remineralization, e.g., by enhancing the patient’s oral hygiene or fluoridation. Nevertheless, in uncooperative patients with cavitated proximal lesions, this approach has significant drawbacks. Methodology: A total of 508 dentists filled the online survey, which was distributed using social media and emails. Online questionnaire was constructed consisting of questions related to demographic data followed by questions linked to their knowledge and perception of Resin Infiltration use among their patients. Results: Overall knowledge reported by the participants regarding Resin Infiltration was 25.2% poor, 72.9% moderate and only 1.9% excellent. 64% of the dental professionals knew that RI is a micro-invasive procedure. Conclusion: It can be concluded from the findings that the knowledge of Riyadh based dental professionals regarding the use, indication and technique of Resin Infiltration is not satisfactory.