Organochlorine pesticides (OCPs) are persistent pesticides whose usage have been banned or restricted worldwide and the presence of its residues in vegetables could affect its nutritional quality as well cause adverse health effects. This study quantified the OCP residue levels in commonly grown and consumed vegetables and assessed the carcinogenic and non-carcinogenic health risks from the consumption of the contaminated vegetables. The OCP residues levels in the extract from the vegetables were determined using a Gas Chromatograph coupled with Electron Capture Detector (GC-ECD). Health risk estimates were analysed using Estimated Average Daily Intake (EADI), Hazard Index (HI), and Hazard Ratio (HR) for children (16.7 kg) and adults (60 kg) weight categories. The residue analysis indicated that amaranths had the highest mean concentration of endrin aldehyde (2.987 AE 0.391 mg kg-1) and endosulfan sulfate (0.661 AE 0.280 mg kg-1), while in fluted pumpkin, the highest mean concentrations were endrin aldehyde (3.491 AE 0.376 mg kg-1) and endosulfan sulfate (2.775 AE 0.644 mg kg-1). The percentage of the detected OCP residues above Maximum Residue Limits (MRLs) ranged from 25% to 100% for both vegetables. Non-carcinogenic health risk estimates for the children weight category showed that aldrin, dieldrin, endrin, endrin aldehyde, and heptachlor detected in both vegetables had HI > 1. While for adults, only aldrin, dieldrin, endrin, and endrin aldehyde revealed non-carcinogenic effect in both vegetables. Human risk estimations for the carcinogenic health effect for the two vegetables showed that aldrin and dieldrin could pose carcinogenic health risks to adult, while aldrin, dieldrin, heptachlor and heptachlor epoxide could pose carcinogenic health risks to children. The results revealed both non-carcinogenic and carcinogenic health risks for the consumers of the contaminated vegetables from the selected locations in Southwestern Nigeria.

Despite the fact that several cases of unsafe pesticide use among farmers in different parts of Africa have been documented, there is limited evidence regarding which specific interventions are effective in reducing pesticide exposure and associated risks to human health and ecology. The overall goal of the African Pesticide Intervention Project (APsent) study is to better understand ongoing research and public health activities related to interventions in Africa through the implementation of suitable target-specific situations or use contexts. A systematic review of the scientific literature on pesticide intervention studies with a focus on Africa was conducted. This was followed by a qualitative survey among stakeholders involved in pesticide research or management in the African region to learn about barriers to and promoters of successful interventions. The project was concluded with an international workshop in November 2021, where a broad range of topics relevant to occupational and environmental health risks were discussed such as acute poisoning, street pesticides, switching to alternatives, or disposal of empty pesticide containers. Key areas of improvement identified were training on pesticide usage techniques, research on the effectiveness of interventions targeted at exposure reduction and/or behavioral changes, awareness raising, implementation of adequate policies, and enforcement of regulations and processes.

No abstract

The study assessed the levels of organochlorine pesticides (OCPs) in eight brands (A-H) of regularly consumed maize-based complementary/breakfast foods in Nigeria. We also evaluated the dietary exposure of infants and young children to the detected OCPs. The OCP residues were quantified using GC-ECD. A total of 10 OCPs residues (β-HCH, δ- HCH, heptachlor, endosulfan sulfate, aldrin, endrin, dieldrin, p,p’ -DDE, p,p’ -DDT and methoxychlor) were detected. Total OCPs burden was highest in brands F, D, and G with mean concentrations of 45.98 mg kg −1 , 28.54 mg kg −1 and 21.87 mg kg −1 , respectively and the lowest burdens in brands H (1.72 mg kg −1 ) and A (6.61 mg kg −1 ). Hazard index (HI) for all the age categories were >1 and all the 6 carcinogens (β-HCH, heptachlor, aldrin, dieldrin, p,p’ -DDE, and p,p’ -DDT) identified had cancer risk index range of 5.43 × 10 −4 to 2.05 × 10 −6 which were above acceptable risk. These results indicated the possibility of both systemic and cancer risks to infants and children consumers of the foods. Food brands manufacturers need to carry out regular pesticide residues analysis of raw materials especially maize prior to the production in order to ensure food safety and quality.

Background. Fluted pumpkin ( Telfairia occidentalis ) and amaranth ( Amaranthus spp.) are common leafy vegetables produced and consumed in southwestern Nigeria. These vegetables attract insect pests which are controlled by pesticides that may have adverse impacts on human health. Objectives. To determine the levels of dichlorodiphenyltrichloroethane (DDT) and hexachlorocyclohexane (HCH) pesticide residues in the two vegetables and evaluate the potential health risks associated with their consumption. Methods. The pesticide residue levels were quantitatively and qualitatively determined using a gas chromatograph coupled with electron capture detector. Health risk assessment were performed using estimated average daily intake and hazard indices for two weight categories: children (16.7 kg) and adults (60 kg). Results. The results showed that delta -HCH, DDT and methoxychlor were predominantly detected in the two vegetables from both farms and markets. In amaranth, the mean concentration of methoxychlor, DDT and delta -HCH were 4.590 ± 2.774 mg/kg (dry weight (dw)), 0.757 ± 0.457 mg/kg (dw) and 0.577 ± 0.390 mg/kg (dw), respectively, while fluted pumpkin levels were 6.223 ± 2.489 mg/kg dw (methoxychlor), 0.504 ± 0.056 mg/kg dw ( delta -HCH) and 0.486 ± 0.123 mg/kg dw (DDT). The levels of HCH and DDT residues were generally above the United Kingdom/European Commission maximum residue limit. The analysis of health risk estimates for non-carcinogenic risk revealed that for both vegetables, the hazard quotient for p, p′ DDT and methoxychlor was >1 for both children and adults. The health risk estimates for carcinogenic risk revealed that hazard indices values were >1 for children for both vegetables and alpha -HCH had a hazard index >1 for adults for amaranth. This means the residue exceeds acceptable standard and present potential risk to consumers of these vegetables. Conclusions. The results obtained from the present study indicate that consumption of amaranth contaminated with alpha -HCH could pose a carcinogenic risk for adult consumers. The consumption of the two vegetables could pose both non-carcinogenic and carcinogenic health risks to children and adults. Therefore, there is need for strict enforcement of regulations on pesticide usage to minimize human health risks. Competing Interests. The authors declare no competing financial interests.