Background: There has been delay evident in diagnosing the drug resistance and non-initiation of appropriate treatment based on drug susceptibility pattern resulting in poor treatment outcome of drug-resistant tuberculosis (DR-TB). Aims and Objectives: The aims of this study were to examine the treatment outcomes for DR-TB patients following universal drug susceptibility testing (UDST) and to examine the association of sociodemographic, behavioral factors, or comorbidities with outcome. Materials and Methods: A retrospective study at a nodal DR-TB center was done for the past 2 years (2018–2019) following the district’s adoption of UDST. The study comprised patients registered between January 2018 and December 2019. Transferred out cases were excluded from the analysis. Cured or treatment completed were assigned as successful, whereas the treatment failed, lost to follow-up or died were adverse treatment outcome. Results: A total of 201 patients were initiated on suitable DOTS regime and they continued the treatment from the center, during the study period. Altogether 129 (64.2%) patients had successful treatment outcome. None of the examined variable (age, sex, SES, Body mass index, and comorbidity) is found to have statistically significant association with outcome (P>0.05). Conclusion: The UDST may be the reason for success rate shown here, higher than in literature published. Although a better stance is possible only by comparing the treatment outcome of pre- and post-uptake of UDST from same setting.

Background: Psychological well-being (PWB) is affected by age, physical health, personality, life experiences, socioeconomic status, and culture. Age is an important social determinant of health and age-based analysis is necessary to rectify one’s health and health care. Aims and Objectives: This study aims to assess the PWB of college students and to determine the correlation between age and PWB aspects. Materials and Methods: This cross-sectional study was conducted among 210 college students selected by simple random sampling. Ryff’s PWB scale, a 42-item version used for the assessment of PWB, and data were collected by self-administering questionnaires. Statistical Analysis: Internal consistency of the scale was estimated and descriptive statistics, independent samples t-test, and regression analysis were applied. Results: The mean age of the participants was 19.41±1.69 years and 61% were male. Cronbach’s alpha coefficient for internal consistency of Ryff’s PWB scale was 0.814 in this study. The mean of PWB was 205.42±11.04 and ≥20 years scored higher in all the parameters of PWB than <20 years, differences were (t=3.62, P=0.001) significant. Simple linear regression showed that age was a highly significant (P=0.002) predictor of PWB. Conclusion: The study illustrated that students of 20 years or more had better PWB in terms of all dimensions than <20 years-, and also suggested the need for future research, like, to deepen on the conceptual and relations between age and PWB, and to analyze the impact that social changes have toward age group on PWB.

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Introduction: Coronavirus Disease (COVID-19) outbreak is one of the biggest medical challenges to humankind in recent times, started from China in December 2019, and had spread to almost all the countries of the world. The social, psychological and economic fissures exposed by the pandemic resulted in mass disruption in human behaviour population. This is pushing them towards more stress. Aim: To analyse the anxiety and depressive symptoms in COVID-19 positive patients. Materials and Methods: A cross-sectional study was conducted on 325 COVID positive patients who were admitted in isolation ward in Tertiary Care Centre and were enrolled in this study, out of which 18 subjects refused to give the consent and 5 were already taking psychiatric medications and were excluded. Telephonic contact was not established with rest of the 5 patients. After ethical clearance, the anxiety and depressive symptoms were assessed by using Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Depression Rating Scale (HAM-D). Results: Maximum patients belonged to age group of 21-40 years (54.9%). Maximum patients were males (70%). Almost 3/4th of the population 64% had depressive symptoms of different severity and 61% had anxiety symptoms. Significant association of anxiety symptoms was seen with gender (p=0.001) and marital status (p=0.002). No association with depressive symptoms was seen with gender (p=0.087) and marital status (p=0.399). Conclusion: COVID-19 had significant impact on the patients. More than half of the population had showed the psychological issues in the form of anxiety and depression. Males and married patients were affected more with both anxiety and depressive symptoms.

Background: Health-care providers played a crucial role in responding to the public health emergency due to COVID-19 pandemic. Therefore, our study aimed to assess depression, anxiety, and stress (DAS) levels among the health-care providers in a COVID-19 dedicated health-care facility. Methodology: From the month of August to December 2020, a cross-sectional study was conducted on health-care providers who were involved in providing health-care services to COVID-19 patients in a tertiary care institute of Jabalpur by purposive convenient sampling through online Google Forms. The study tool used was validated depression, anxiety, and stress scale-21 having a good internal consistency having Cronbach's alpha value 0.85. Results: From 112 health-care providers, higher level of anxiety was found (29.46%) followed by depression (17.85%) and stress (16.07%). Mild, moderate, severe, and extremely severe anxiety were found in 18.75%, 7.14%, 1.78%, and 1.78%, respectively. Mild and moderate depression were found in 9.82% and 8.03%. Mild, moderate, and severe stress were found in 8.92%, 6.25%, and 0.89% of health-care providers, respectively. A significant association of depression, stress, and anxiety with designation of the participants was found (P < 0.001). Conclusion: To combat DAS, it is necessary to cascade awareness and knowledge should be disseminated. Regular screening of health-care providers, counseling, and stress management programs should be conducted.