No abstract

Aim:The aim of the present study is to evaluate the efficacy of curcumin gel as local drug delivery post-scaling and root planing and its effect on clinical parameters like plaque, gingival scores, pocket depth, and clinical attachment level (CAL). Materials and methods: Ten patients with two sites in the contralateral quadrants having probing pocket depths (PPDs) of ≥5 mm were selected. Full-mouth scaling and root planing (SRP) was performed followed by the application of curcumin gel on a single side. Assessment of plaque index (PI), gingival index (GI), PPD, and CALs were done at the baseline and at the 4th week. Results: The results revealed that there was a statistically significant reduction in PI and probing depth in the test group when compared with the control group. CAL was improved but the results were not statically significant. Conclusion:The local application of curcumin gel when used in conjunction with SRP showed a significant improvement in periodontal parameters and has a beneficial effect in patients with chronic periodontitis. Clinical significance: Curcumin gel as an adjunct to SRP showed a marked improvement in restoring gingival health by an improvement in clinical parameters. It has proven properties like anti-inflammatory, antioxidant, antimicrobial, hepatoprotective, immunostimulant, antiseptic, antimutagenic, and it also accelerates wound healing. It may be a more acceptable and viable option for the common man. Curcumin can be used as an effective alternative local drug delivery agent.

Background:Schizophrenia is a psychosis characterized by delusions and hallucinations occurring in clear consciousness. Studies have shown that the cytokines may modulate dopaminergic metabolism and schizophrenic symptomatology in schizophrenia. Cytokine involvement in periodontal disease is also well documented. To date, however, there has been relatively little research assessing periodontal status of patients with schizophrenia. The present study was therefore mainly intended to understand the exact link, if any, between periodontal disease and schizophrenia.Materials and Methods:A total of 250 schizophrenic patients (140 males and 110 females), between 25 and 55 years of age, were selected from the out patient department of National Institute of Mental Health and Neural Sciences, Bangalore and their periodontal status was assessed as part of this cross-sectional epidemiological survey.Results:ANOVA showed that there was increased evidence of poor periodontal condition, as evidenced by gingival index and plaque index in patients who had been schizophrenic for a longer duration of time (P < 0.001). So also, higher probing pocket depths were found in schizophrenics suffering from a longer period of time than others (P < 0.001).Conclusions:Although oral neglect might be a cause of poor periodontal health in schizophrenics, the possible link between periodontal diseases giving rise to schizophrenia cannot be overlooked due to the presence of cytokine activity which is present both in schizophrenia and periodontal disease.

Crop yield forecasting is critical for enhancing food security and ensuring an appropriate food supply. It is critical to complete this activity with high precision at the regional and national levels to facilitate speedy decision-making. Tea is a big cash crop that contributes significantly to economic development, with a market of USD 200 billion in 2020 that is expected to reach over USD 318 billion by 2025. As a developing country, Bangladesh can be a greater part of this industry and increase its exports through its tea yield and production with favorable climatic features and land quality. Regrettably, the tea yield in Bangladesh has not increased significantly since 2008 like many other countries, despite having suitable climatic and land conditions, which is why quantifying the yield is imperative. This study developed a novel spatiotemporal hybrid DRS–RF model with a dragonfly optimization (DR) algorithm and support vector regression (S) as a feature selection approach. This study used satellite-derived hydro-meteorological variables between 1981 and 2020 from twenty stations across Bangladesh to address the spatiotemporal dependency of the predictor variables for the tea yield (Y). The results illustrated that the proposed DRS–RF hybrid model improved tea yield forecasting over other standalone machine learning approaches, with the least relative error value (11%). This study indicates that integrating the random forest model with the dragonfly algorithm and SVR-based feature selection improves prediction performance. This hybrid approach can help combat food risk and management for other countries.

Two most common conditions that can independently lead to tooth mortality are periodontal and pulpal diseases� To maintain the natural dentition and also to restore the lost periodontium are the goal of endodontic and periodontal therapy� There are several reviews in literature where authors have given wide information about the etiology, pathogenesis, classification, diagnosis, and treatment planning, and lot of literature about the recent advances pertaining to aspects of endo-perio lesions are also available, but reviews compiling all major aspects are relatively less and this review aims to brief the etiology, various classifications, diagnosis, and management of endodonticperiodontic lesions� Successful treatment of periodontic-endodontic lesions depends on all contributing lesions being treated� Lesions with combined etiology will require both endodontic and periodontal therapy. Endodontic therapy should be completed first. The clinical experience and acumen of the dentist must be of the highest degree to enable choosing the procedure that will bring healing with the appropriate intervention�