Introduction:-Calprotectin is calcium binding protein which is secreted by neutrophils & monocytes. It is found both in plasma & in stools. It is predominantly elevated in inammatory conditions such as inammatory bowel disease (IBD). To a certain extent, it is also elevated in infectious conditions & in polyposis. This study was conducted to evaluate diagnostic precision of fecal calprotectin in known inammatory bowel disease (IBD) patients A retrospect Method:- ive analysis of calprotectin, ASCA, cANCA, pANCA, Total WBC count, ESR, CRP was obtained in referral laboratory in Mumbai over a span of 4 years (2018-2022). Prevalence of raised Results:- calprotectin was signicantly seen in 13-18 years age group. (P<0.0001). Calprotectin showed a positive correlation with WBC count, CRP & ESR. There was no signicant association between calprotectin levels & gender. Fecal calprotectin can be used not only in research Conclusion:- but also in routine clinical practice in differentiating between patients with inammatory & non-inammatory bowel disease. Aims and Objectives: - 1. To study the prevalence of fecal calprotectin levels with respect to different age groups & gender in inammatory bowel disease patients. 2. To establish correlation of fecal calprotectin levels with ANCA, ASCA, Total WBC count, ESR &CRP

Introduction: - Anemia is major health problem which affects children, women of reproductive age groups to a signicant extent. This study was done to study prevalence of anemia in Mumbai across different age groups. Aims And Objectives: - To study prevalence of nutritional anemia in Mumbai with respect to age group & gender To compare prevalence of vitamin B12 deciency anemia with iron deciency anemia To establish correlation between RBC indices with serum Iron & Serum B12 levels Method: - We did a retrospective analysis of serum iron prole, CBC, Vitamin B12, Folic acid data obtained in referral laboratory in Mumbai over a span of 3 years (2019-2021). Population studied belonged to Mumbai metropolitan region. CBC was analyzed on DXH Coulter. Serum Iron, serum ferritin, TIBC, Vitamin B12 &serum folic acid were analyzed on Cobas analyzers. We compared & correlated results according to gender & age Results: - Prevalence of low serum Iron & serum ferritin was seen in females as compared to males (P< 0.001). However low levels of vitamin B12 was signicantly seen in males as compared to females (P<0.001). Low serum iron, Ferritin, MCH, MCV and high TIBC were signicantly associated with low Hemoglobin (P<0.001)

Introduction:Autoimmune thyroid disorder is the most common cause of hypothyroidism seen in adults. Anti-TPO and anti-TG play a vital role in lab diagnosis of autoimmune thyroid disorder. In our present study we have tried to establish a correlation between anti-TPO & anti-TG levels with various thyroid parameters Aims and Objectives: Ÿ To study prevalence of Anti-thyroid antibodies, which are specic for autoimmune thyroiditis, in deranged thyroid prole across Indian population Ÿ To study prevalence of Anti-TPO antibodies across adult population Ÿ To establish co-relation between TSH level and Anti-TPO antibody value Method: We did a retrospective analysis of Thyroid Prole data obtained at a referral laboratory based in Mumbai over a span of 6 years (2016-2021). Population studied belonged to the city of Mumbai metropolitan region. The separation and quantication of T3, T4, TSH, FT3, FT4, ATG & TPO in serum was done on the Cobas e-411/e-601/e801analysrs. Total of 3342 cases were studied in the age group of 18 years - 60years. We compared & correlated results according to gender and age. Results: The incidence and prevalence of ATG and TPO antibodies were more in females as compared to males. For TPO antibodies P value being 0.0013 and for ATG antibodies, P value being 0.0002 Anti-TPO level had positive correlation with ATG level. (Coefcient of correlation 0.3285) (P value-0.0001). Also Anti-TPO antibodies had positive correlation with TSH levels (Coefcient of correlation 0.2207) (P value 0.0001) Conclusion: Anti-TPO antibodies are commonly associated with thyroid dysfunction followed by Anti-TG antibodies. They are most commonly seen in 36-45 years of age group.