Thromboangitis obliterans or Buerger's disease is a segmental inflammatory condition of small and medium-sized arteries and veins. It is commonly seen in males with age under 45 years and with a current or recent history of tobacco use, and in smokers. It is sporadic in young women. This report describes a primigravida with dry gangrene in both upper and lower limbs because of Buerger’s disease. The primary diagnosis of the disease occurred first time in pregnancy at the 17th week of gestation with the patient reporting dry gangrene and pain in the digits and confirmed with a non-invasive Doppler study. The patient was screened for autoimmune diseases, diabetes mellitus, and the presence of hypercoagulable disorders. Echocardiography and arteriography were performed to rule out any source of emboli. The case report aims to discuss a rare diagnostic and therapeutic dilemma in the case of a pregnant woman presenting with gangrene without any history of tobacco addiction.

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Radiomics have shown great promise for integrated healthcare. Radiomics is defined as high-performance retrieval of significant volumes of characteristics from images and conversion of images to higher-dimensional data and subsequently mining for improved support for therapeutic judgements. It has its roots within Computer-Aided Detection (CAD)or Computer-Aided Diagnosis (CADx); it is unique in many aspects. It does not just detect and diagnose but also ventures into therapeutic, prediction, projection and modelling that can be used to generalize and reproduced. It has great potential in creating a paradigm shift in the way healthcare is delivered and perceived. We will review and outline the stage of radiomics& its SWOT analysis, exclusively addressing application in medical imaging and spotlighting the technical issues.

Background: Doppler study of uterine and fetal vessels assesses the feto-maternal circulation. An abnormal Doppler study is a sign of placental dysfunction and fetal damage. This study aims to study the relationship of Doppler velocimetry of the uterine artery, umbilical artery, and middle cerebral artery to perinatal outcomes in normal and high-risk pregnancies.Methods: A prospective cohort study was conducted in a tertiary health care center. A total of 150 patients aged 18–35 years with the gestational age of 28 to 40 weeks in 2 cohorts, 75 in high risk and 75 in the non-high-risk cohort were included. Pregnant women with gestational hypertension, intrauterine growth restriction, preeclampsia, preeclampsia plus IUGR were included in high-risk cohort. Doppler study was carried out, data was collected, and was analyzed.Results: Doppler parameters and their association with perinatal outcome were measured. The sensitivity of umbilical artery index (79.4%) was found to be highly predictive of poor neonatal outcomes compared to middle cerebral artery Doppler (58.8%) and cerebroplacental ratio (41.2%) parameters. A high positive predictive value for unfavourable perinatal outcomes with an accuracy of 93% using umbilical artery indices, 95% using MCA Doppler, and 93% CPR was found in the study. Specificity of umbilical artery Doppler was 87.5%, MCA Doppler was 93.75% and CPR was 93.75%.Conclusions: When incorporated into evaluating high-risk pregnancies complicated by pregnancy-induced hypertension, preeclampsia, and IUGR in the third trimester, screening the fetuses for well-being with Doppler helps in timely intervention and improves the perinatal outcome.