Multimodal non-linear microscopy combining coherent anti-Stokes Raman scattering, second harmonic generation, and two-photon excited fluorescence has proved to be a versatile and powerful tool enabling the label-free investigation of tissue structure, molecular composition, and correlation with function and disease status. For a routine medical application, the implementation of this approach into an in vivo imaging endoscope is required. However, this is a difficult task due to the requirements of a multicolour ultrashort laser delivery from a compact and robust laser source through a fiber with low losses and temporal synchronization, the efficient signal collection in epi-direction, the need for small-diameter but highly corrected endomicroobjectives of high numerical aperture and compact scanners. Here, we introduce an ultra-compact fiber-scanning endoscope platform for multimodal non-linear endomicroscopy in combination with a compact four-wave mixing based fiber laser. The heart of this fiber-scanning endoscope is an in-house custom-designed, single mode, double clad, double core pure silica fiber in combination with a 2.4 mm diameter NIR-dual-waveband corrected endomicroscopic objective of 0.55 numerical aperture and 180 µm field of view for non-linear imaging, allowing a background free, low-loss, high peak power laser delivery, and an efficient signal collection in backward direction. A linear diffractive optical grating overlays pump and Stokes laser foci across the full field of view, such that diffraction-limited performance is demonstrated for tissue imaging at one frame per second with sub-micron spatial resolution and at a high transmission of 65% from the laser to the specimen using a distal resonant fiber scanner.
We present a novel approach to directly measure the bend loss of individual modes in few-mode fibers based on the correlation filter technique. This technique benefits from a computer-generated hologram performing a modal decomposition, yielding the optical power of all propagating modes in the bent fiber. Results are compared with rigorous loss simulations and with common loss formulas for step-index fibers revealing high measurement fidelity. To the best of our knowledge, we demonstrate for the first time an experimental loss discrimination between index-degenerated modes.
A structured sapphire-derived all-glass optical fiber with an aluminum content in the core of up to 50 mol% was used for fiber Bragg grating inscription. The fiber provided a parabolic refractive index profile. Fiber Bragg gratings were inscribed by means of femtosecond-laser pulses with a wavelength of 400 nm in combination with a two-beam phase mask interferometer. Heating experiments demonstrated the stability of the gratings for temperatures up to 950°C for more than 24 h without degradation in reflectivity.
We report on the first, to the best of our knowledge, implementation of a fluorine co-doped large-mode-area REPUSIL fiber for high peak power amplification in an ultrashort-pulse master oscillator power amplifier. The core material of the investigated step-index fiber with high Yb-doping level, 52 µm core and high core-to-clad ratio of 1:4.2 was fabricated by means of the REPUSIL powder-sinter technology. The core numerical aperture was adjusted by fluorine codoping to 0.088. For achieving high beam quality and for ensuring a monolithic seed path, the LMA fiber is locally tapered. We demonstrate an Yb fiber amplifier with near-diffraction-limited beam quality of
M
2
=
1.3
, which remains constant up to a peak power of 2 MW. This is a record for a tapered single core fiber.
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