(1) Background: We present the protocol of a randomized controlled trial designed to evaluate the benefit of a novel clinical decision support system for the management of patients with COVID-19. (2) Methods: The study will recruit up to 500 participants (250 cases and 250 controls). Both groups will receive the conventional telephone follow-up protocol by primary care and will also be provided with access to a mobile application, in which they will be able to report their symptoms three times a day. In addition, patients in the active group will receive a wearable smartwatch and a pulse oximeter at home for real-time monitoring. The measured data will be visualized by primary care and emergency health service professionals, allowing them to detect in real time the progression and complications of the disease in order to promote early therapeutic interventions based on their clinical judgement. (3) Results: Ethical approval for this study was obtained from the Drug Research Ethics Committee of the Valladolid East Health Area (CASVE-NM-21-516). The results obtained from this study will form part of the thesis of two PhD students and will be disseminated through publication in a peer-reviewed journal. (4) Conclusions: The implementation of this telemonitoring system can be extrapolated to patients with other similar diseases, such as chronic diseases, with a high prevalence and need for close monitoring.

Digital game-based learning (DGBL) is a novel methodology implemented in many educational virtual settings to improve students´ attention, motivation, and engagement while learning. This chapter aims to provide insight into how game-based methods can enhance students' learning process with sensory, intellectual, and learning disabilities. Specifically, the key of this chapter is to assess the possibilities offered by the introduction of DGBL in educational contexts from a theoretical perspective to understand better the range of opportunities that it can mean for learning and, therefore, for the personal and professional development of people with sensory, intellectual, and learning disabilities.

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