Limited information is available concerning the coexistence of COVID-19 and opportunistic infections in people living with HIV. The possible association of COVID-19 with AIDS-related respiratory diseases should be considered, particularly in patients with advance immunosuppression. We report the case of a male patient with AIDS-related disseminated histoplasmosis associated with COVID-19.

Background: Due to overlap ways of transmission, HIV and hepatitis C (HCV) co-infection is highly prevalent. The aim of this study was to characterize the HCV cascade of care among HIV/HCV infected individuals in a major HIV center in Buenos Aires, Argentina.Methods & Materials: Data was drawn from Electronic Medical Records of HIV/HCV co-infected individuals. We assessed the number and proportion of patients achieving each step of the HCV cascade: RNA confirmation, fibrosis staging, treatment initiation, treatment completion, and sustained virological response (SVR).Results: Of the estimated 1650 HIV/HCV co-infected individuals, only 803 (49%) were actually tested for HCV antibody. Only 355/1650 (21%) were tested for HCV-RNA, of whom 320 were positive, confirming chronic infection (90%). Meanwhile, 46/1650 (3%) had only fibrosis staging. Among the 320 patients with positive RNA, 243 (76%) underwent fibrosis staging, and in 119 (37%) treatment was prescribed. Of them, 42 (35%) had received interferon-based therapy (the only drugs available before 2016), 34 (29%) received direct-acting antivirals (DAA), and 43 (36%) are going to initiate treatment with DAA this year. Among the 76 patients that completed treatment, 57 (75%) achieved SVR. Of the 34 individuals who received DAA, 100% achieved SVR. Conclusion:In accordance to what has been reported worldwide, we observed gaps in our HCV care cascade. In particular, large gaps were documented at the diagnostic stages, with less than a quarter actually receiving RNA confirmation. These results highlight the need to identify and address barriers that are preventing our HCV/HIV co-infected populations from benefitting from highly efficacious newer DAA-based treatments. It is crucial to generate awareness about the importance of active search of HCV coinfection in HIV patients, and the steps required to complete HCV evaluation and treatment. This goal can mainly be achieved by a continuous medical and patient education.

El absceso de músculo psoas iliaco se considera una rareza. Su detección ha mejorado con la utilización de imágenes como la tomografía computada o la resonancia magnética.Presentamos una revisión de casos de absceso de psoas-iliaco internados entre julio de 2015 y febrero de 2018 en un hospital de CABA, Argentina.En este periodo se diagnosticaron un paciente considerado de origen primario y ocho de origen secundario. Se observó predominio de colecciones asociadas a espondilodiscitis. El síntoma más frecuente fue la fiebre. Staphylococcus aureus fue el germen más rescatado en muestras microbiológicas.Se debe tener alto índice de sospecha de esta patología ante la presencia de fiebre, dolor lumbar y en ocasiones alteración de la marcha. El empleo de antibióticos de amplio espectro sumado a la evacuación de colecciones constituyen la estrategia más efectiva.

Acute HIV infection presenting as severe opportunistic disease is a very uncommon event associated with more rapid HIV progression and higher mortality. We describe the case of a patient with cryptococcal meningitis in the setting of primary HIV infection.

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