Confluent and reticulated papillomatosis of Gougerot-Carteaud (CARP) is a rare dermatosis. Even though many authors affirm that it is a keratinization disorder, the causes are still unknown. There are various therapeutic options to treat this disorder: retinoids, antibiotics, keratolytic, and others, but the results are unsatisfactory. This study presents the case of two identical twins, approaching clinic characteristics, as well as histopathologic characteristics, and the difficulties of finding the correct diagnosis since it is a rare disease.