Background-Low-dose dobutamine challenge (DSMR) by MRI was compared with delayed enhancement imaging with Gd-DTPA (SCAR) as a predictor of improvement of wall motion after revascularization (RECOVERY). Methods and Results-In 29 patients with coronary artery disease (68Ϯ7 years of age, 2 women, 32Ϯ8% ejection fraction), wall motion was evaluated semiquantitatively by MRI before and 3 months after revascularization. SCAR and DSMR were performed before revascularization. The transmural extent of scar was assessed semiquantitatively.
Purpose: Many surgeons assume 3-stage ileal pouch-anal anastomosis (IPAA) is safer than 2stage IPAA in patients with active ulcerative colitis (UC), although recent data suggest outcomes are comparable. This study aimed to compare perioperative complications, late complications, and functional outcomes after 2-versus 3-stage IPAA in patients with active UC. Methods: A retrospective review was conducted of patients who underwent 2-or 3-stage IPAA for active UC from 2000-2015 in a high-volume institution. Patients completed quality of life surveys six months following ileostomy reversal. Perioperative and late complications were recorded. Outcomes were compared with the Fisher Exact test, and multivariable logistic regression was used to adjust for potential confounders. Results: We identified 212 patients who underwent 2-or 3-stage IPAA for active UC, of whom 157 patients (74.1%) underwent 2-stage procedures and 55 (25.9%) underwent 3-stage procedures. More patients undergoing 2-stage procedures were taking immunomodulators preoperatively (46.3% vs. 23.1%, p=0.01), but there was no difference in use of steroids (p=0.09) or biologic agents (p=0.85). Three-stage procedures were more likely to be urgent (78.6% vs. 30.2%,
Pulmonary venous flow diastolic deceleration time is an appropriate non-invasive measurement to stratify patients with respect to elevation of left ventricular end-diastolic pressures.
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