Phrygian cap anomaly occurs in 4% of the general population due to a fold in the gallbladder wall. Cholecystitis with gallstones is a potential complication, which can be associated with cholestasis. An asymptomatic case of this condition is herein described in a 71-year-old man. Diagnosis was incidental, based on the images of an ultrasound scan performed during a routine checkup. Because polyps were suspected, he underwent a prophylactic laparoscopic cholecystectomy. A microscopic study of the gallbladder detected cholecystitis with cholelithiasis and ruled out the presence of polyps. The role of polyps and of routine gallbladder histopathology in cancer is discussed.

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