OBJECTIVEImaging plays a central role in the management of selected cases of acute pancreatitis and its complications, complementing laboratory investigations such as serum amylase and lipase levels that have relatively high sensitivity and specificity. In addition to clinical signs and laboratory investigations, imaging helps in confirming the clinical diagnosis when there is uncertainty and elucidates the cause and grade the extent and severity of acute pancreatitis. It also aids in the early detection of complications. MATERIAL AND METHODSUltrasound and CECT Abdomen were done in 55 patients with a typical clinical suspicion of acute pancreatitis. The findings were correlated with biochemical parameters and the discrepancy between the two modalities i.e. USG and CT was evaluated. RESULTSAbout 55 cases were studied and they were subjected to USG and CT (plain and contrast). Most of the patients were males with male to female ratio 13:1. Most common aetiology was chronic alcohol consumption (42 cases, 76.33%) followed by idiopathic (11 cases, 20%) and trauma (2 cases, 3.66%). Multiple sites of involvement (35 cases, 63.65%) was more common than focal involvement of pancreas. Severe form of pancreatitis (37 cases, 67.27%) was the most common type according to MCTSI. The most common complication was ascites (cases, 56.36%) and pleural effusion (16 cases, 29.09%). CONCLUSIONThe sensitivity of USG in detecting acute pancreatitis was 41.8%. The sensitivity of CT (plain and contrast) in detecting pancreatitis was 100%. Modified CT severity index shows significant correlation between severity of pancreatitis and patient outcome. Serum lipase is more accurate in detecting acute pancreatitis than serum amylase. Thus, from the present study, it can be concluded that CT (plain and contrast) is superior in detecting and evaluating pancreatitis. Hence, CT plain and contrast should be performed in all cases of clinically suspected pancreatitis especially with positive serological findings.

BACKGROUNDWhite matter disorders or leukoencephalopathies comprise all disorders that exclusively or predominantly affect the white matter of the brain. There are many different leukoencephalopathies, which can occur at all ages, be progressive or static and be genetic or acquired. [1] Leukodystrophies are genetically determined leukoencephalopathies. The diagnostic workup is complicated. MRI has proven to be pivotal in the diagnostic workup of patients with leukoencephalopathies. [2]