Introduction: This study explored the psychometric properties of the modified Harris Hip Score-Greek version (mHHS-Gr) as a patient-reported outcome (PRO) measure in osteoarthritic hip patients. Methods: Internal consistency, test-retest reliability and reproducibility were evaluated in 90 patients aged >55 years. Construct validity was tested against Greek versions of the Lower Extremity Functional Scale (LEFS-Greek) and WOMAC Index (WOMAC-Gr), and the Timed Up and Go (TUG) and 9-stairs-ascend/descend (9S-A/D) tests. Known-groups validity was examined using TUG score (cut-off 13.5 s) as an estimate variable. Responsiveness was examined before and 4 weeks after direct anterior minimal invasive surgery. Results: Reliability: Internal consistency was moderate (Cronbach’s a = 0.614, p < 0.001). Test-retest reliability was excellent (ICC = 0.881, 95% CI, 0.824–0.920). Reproducibility: Floor and ceiling effects were both 1.1%; measurement error was 3.54 ( p < 0.05); minimal important change was lower than minimal detectable change. Validity: mHHS-Gr correlated strongly with both LEFS-Greek and WOMAC-Gr (Pearson’s r 0.801 and −0.783, respectively; p < 0.001). The questionnaire’s correlations with TUG and 9S-A/D were also significant but moderate (Spearman’s ρ: −0.547 and −0.575, respectively; p < 0.001). Known-groups validity showed that mHHS-Gr scores were significantly higher in participants with TUG < 13.5 seconds than in those with TUG > 13.5 seconds ( p < 0.001). In ROC analysis, the cut-off point of 52.5 yielded sensitivity 81% and specificity 71%. Responsiveness: Standardised response mean and Guyatt’s responsiveness statistic were greater than 0.8. Discussion: mHHS-Gr showed significant moderate to excellent reliability, significant moderate to strong validity properties and excellent responsiveness. Overall, mHHS-Gr could be a reliable and valid PRO measure for assessing patients with osteoarthritis of the hip.

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