There are a wide number of digestive system disorders, which impose a substantial influence on morbidity and mortality rates, worldwide. Ethno medicinal plant studies have become of particular interest and have become increasingly more valuable in the development of health care and conservation programs in different parts of the world. In developing countries, medicinal plants continue to be a main source of medication. It has been estimated that approximately 88% of the inhabitants of underdeveloped countries rely mainly on traditional medicine for their primary form of medicinal health care. This review investigates the available studies on the pharmacological effects of some medicinal plants (Aloysia triphlla, Citrus aurantium, Echium amoenum, Lavandula stoechas, Melissa officinalis, Valeriana officinalis, Viola odorata, Salix aegyptica and Cinnamomum zelanicum) on digestive diseases. The present article incorporated a detailed interpretation of the these nine medicinal plants, emphasizing its therapeutic uses, pharmacological properties and mechanism of action based on preclinical and clinical studies, safety issues along with the current research potential of the medicinal plants.