An excess of maternal androgen adversely affects the implan tation process and contributes to uterine circulatory disturbances and myometrium vessel sclerosis. Placental insufficiency is typi cally diagnosed at the end of the second trimester of pregnancy or at the beginning of the third trimester, when the treatment is not effective.Many researchers have attempted to use early sonographic diagnostics to identify placental failure in various pathological states. Nevertheless, the peculiarities of the formation of the fetal-placental complex during the first and second trimesters are still undefined. In this study, we traced the process of placental formation under conditions of excess maternal androgen using ultrasound and Dopplerometry. Morphological examinations of the сhorion and placental tissue were undertaken to сompare any changes.Unfavorable chorion locations, heterogeneous chorion tis sue structures, and marginal sinus dilatations were revealed by ultrasound. According to a Dopplerometric investigation, a statistically significant increase in peripheral vessel resistance in cases of hyperandrogenism was identified compared with healthy pregnancies. The negative influence of hyperandrogenism on placental formation was confirmed by morphologi cal data (including the presence of immature decidual cells, defec tive villi that covered the epithelium, and the dissociative development of cotyledons).