Q uality of life (QOL) issues are particularly important for cancer patients. Fatigue, which is generally difficult to treat (1-3), seriously interferes with QOL by substantially diminishing patient ability to carry out meaningful daily activities (4). There is considerable diagnostic confusion over cancer-related fatigue (CRF) in the literature (5). Depending on the sample of patients and the type of measure used, prevalence estimates of fatigue during cancer treatment range from 25% to 99%. Between 17% and 30% of long-term survivors report problems with fatigue for several years after they complete treatment (6). Atkinson and colleagues published a set of guidelines designed to assist in the identification and treatment of CRF (4). Cella and colleagues proposed a set of diagnostic criteria
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