Localised scleroderma is an uncommon connective tissue disease of multifactorial aetiology occurring in the paediatric and adult population. It is relatively difficult to conduct any research on the subject of this disease entity treatment due to the low number of patients suffering from morphea, a tendency of the disease to remit spontaneously, and not yet well recognised aetiology. Hence, there has been developed no causal treatment of well-proven effectiveness, and schedules of symptomatic therapy are not yet clearly determined. The paper depicts most widely used topical treatment methods in morphea therapy, which due to minor risk of systemic adverse effects seem to be a beneficial therapeutic alternative. The main aim of this article was to analyse different topical treatment options used in localised scleroderma therapy and to indicate the most appropriate, safe, and effective one.

Introduction. Octenisept ® is an antiseptic solution which is intended to be applied on the skin, mucous membranes and wounds. Objective. To present a case study of a bullous skin lesions, which occurred in a 4-year-old girl after Octenisept ® application, and to highlight various possible side effects of this preparation. Case report. In a 4-year-old girl Octenisept ® was applied preventively three times at intervals of 12 hours on an epidermal abrasion. Erythema and hydropic papules emerged 6-8 hours after application and were followed by vesicles and bullae 8 hours later. In spite of the topical treatment with glucocorticoids and an antibiotic, the lesions persisted for several weeks. Conclusions. Taking into consideration the wide usage of Octenisept ® in many fields of medicine, there is a need to conduct further research on the allergic potential and toxicity of this product. streszczenie Wprowadzenie. Octenisept ® jest środkiem antyseptycznym przeznaczonym do stosowania na powierzchnię skóry, błon śluzowych i ran. Cel pracy. Przedstawienie przypadku reakcji pęcherzowej skóry u 4-letniej dziewczynki, która wystąpiła po aplikacji Octeniseptu ® na otarty naskórek, oraz zwrócenie uwagi na możliwe działania niepożądane tego preparatu. Opis przypadku. U 4-letniej dziewczynki zastosowano profilaktycznie Octenisept ® , spryskując otarcie naskórka 3-krotnie co 12 godzin. Zmiany skórne w postaci rumienia i grudek obrzękowych pojawiły się po 6-8 Case report/Opis przypadku bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept ®) reakcja pęcherzowa skóry jako przykład niepożądanego działania preparatu zawierającego 0,1% dichlorowodorku oktenidyny i 2% fenoksyetanolu (Octenisept ®

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