Resesi gingiva ditandai dengan terbukanya permukaan akar akibat migrasi marginal gingiva ke arah apikal. Kondisi initerjadi akibat kehilangan perlekatan periodontal. Resesi gingiva dapat terjadi antara lain akibat: kebersihan mulut yangburuk, cara menyikat gigi yang salah, permukaan akar yang menonjol, perlekatan frenulum yang terlalu tinggi dan traumaoklusi. Resesi gingiva umumnya menyebabkan masalah estetik bila terjadi pada gigi anterior atas. Selain itu, resesigingiva cenderung mengakibatkan peningkatan resiko hipersensitif dentin. Perawatan resesi gingiva dapat dilakukanmelalui prosedur bedah dan non bedah. Prinsip dasar perawatan resesi gingiva adalah menutup permukaan akar yangterbuka untuk memperbaiki estetik dan mengurangi hipersensitif dentin.
Some previous studies mentioned that papaya seed extract has anti-inflammatory activity because it contains polyphenols including phenolic and flavonoid acids. Polyphenols of the papaya seed extracts are known to inhibit the severity of periodontitis. It can prevent the release of excessive osteoclastogenesis which may promote bone resorption aggravating periodontitis. Hence, this study aims to determine the role of papaya seed extract in reducing the number of osteoclasts in rats with periodontitis. Twenty-eight male Wistar rats were divided into 4 groups of induced periodontitis using lipopolisakarida (LPS) Porphyromonas gingivalis (P. Gingivalis) and followed by wire ligature in “8” placed around the mandible mandibular incisor. The first group was given standard food without any papaya extract, while each rat in three other groups with periodontitis (P2, P3, P4) was given with Papaya seed extracts of 200 mg/kgBW, 300 mg/kgBW, and 400 mg/kgBW. Seven rats in one group were not induced by periodontitis and were fed with standard food as a control group. On the 30th day, the rat was sacrificed, and its transverse pieces of alveolar bone around the mandibular incisor were stained with Hematoxylin-Eosin. The data analyzed by one way ANOVA indicated a significant result. Thus, it is conclusive that extract of papaya seed ethanol inhibited osteoclastogenesis in Wistar rats induced with periodontitis.
The papaya seed ethanol extract is rich in antioxidant ingredients, such as flavonoids and phenolic acids. One of the main factors causing chronic inflammatory in periodontitis is oxidative stress. Administration of papaya seed extract is assumed to increase the number of rat osteoblast cells induced periodontitis. This research was conducted to analyze the effect of papaya seed extract on osteoblasts cells of rat induced periodontitis. This research represented an experimental laboratory-based investigation involving 35 rats of the Rattus norvegicus strain divided into 5 treatment groups (K, P1, P2, P3, P4). Control group (K) was not induced by periodontitis and was not given an extract, while group P induced periodontitis using LPS Phorphyromonas gingivalis (P.gingivalis) for 7 days and continued wire mesh installation around the mandibular incisors in the form of number “8” for 7 days. P1 group was given feed only without extract, while the rest were given extract of 200 mg/kgBB, 300mg/kgBB, and 400mg/kgBB. The data obtained were analyzed with a one-way ANOVA test. The results showed that the average number of osteoblasts varied significantly between the groups. There was an increase in the average number of osteoblast cells in rat induced periodontitis after given papaya seed extract.
Aim:The aim of this study was to introduce the less invasive vestibule access tunneling in combination with platelet-rich fibrin (PRF) membrane for gingival recession treatment. Materials and methods: Seven subjects with Miller's class I or II buccal gingival recession were selected for this study. All subjects were treated with mucogingival surgery using the less invasive vestibule access tunneling in combination with PRF membrane. Clinical examination performed on each subject and the height of gingival recession was recorded preoperatively (baseline), and at 1 and 3 months postoperatively. The data were statistically analyzed using analysis of variance (ANOVA) with post hoc Tukey's LSD test to determine the significant difference between groups. Statistical significance level was set at 0.05. Results: The results showed that there were significant differences in recession height between baseline and both 1 month and 3 months postoperatively (p < 0.05). Nevertheless, there was no significant difference between 1 and 3 months postoperatively (p > 0.05). All patients reported satisfactory esthetic results both at 1 and 3 months postoperatively. Conclusion: Mucogingival surgery using the less invasive vestibule access tunneling in combination with PRF membrane for gingival recession treatment provided optimal root coverage. Clinical significance: This article introduces a new tunnel technique in combination with PRF membrane for gingival recession treatment. Previous studies tried to make access using the tunnel technique performed through gingival sulcus. In this study, the access is performed through the vestibule region. Access from the vestibule can minimize the damage of gingival margin integrity, especially in patients with thin gingival biotype.
Background: Periodontal disease is a chronic, multi-factorial disease. Chronic periodontitis is one of the main causes of tooth loss. Chronic periodontitis is usually caused by Porphyromonas gingivalis (P. gingivalis). P. gingivalis can induce NFκB activation resulting in the increasing of periodontal extracellular matrix degradation. Curcumin can inhibit NFκB activation and reduce the severity of periodontal degradation. Purpose: This research was aimed to observe level of NFκB in gingival junctional epithelium of rat exposed to Porphyromonas gingivalis with local administration of curcumin. Methods: Sixteen Wistar rat were divided into two groups. Group 1 (treatment) consisted of eight rat given 2 x 10 6 CFU/ml P. gingivalis and 1% curcumin. Meanwhile, group 2 (control) consisted of eight rat given 2 x 10 6 CFU/ml P. gingivalis only. GCF samples were collected from gingival sulcus. The samples were biochemically analyzed with ELISA method. Data were then analyzed statistically by using independent t-test (α=0.05). results: The examination of NFκB level showed that there was significant difference between treatment group and control group (p<0.05). The level of NFκB in the treatment group was significantly lower than the control group. Conclusion: It can be concluded that 1% curcumin application can reduce NFκB level in gingival junctional epithelium of rat exposed to P. gingivalis.
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