Introduction: Mandibular third molars are the most frequently affected by impaction. No previous study had been conducted in the Jazan region. Aim of the study: To evaluate the prevalence and patterns of third molar impaction among the Jazanian subpopulation in the southwestern region of Saudi Arabia. Materials and methods: A retrospective study was conducted involving the analysis of the orthopantomograms (OPG) of 1012 patients who attended the Jazan University College of Dentistry. The OPGs were selected randomly from patient records to examine the frequency and pattern of third molar impaction. Data were analyzed, and p < 0.005 was set as significant. Results: A total of 1012 subjects were included, among whom 550 (54.3%) were males. The largest age group was 18-32 years old and accounted for 533 (52.67%) of the subjects. The number of subjects with impacted tooth/teeth was 668 (66%), and frequencies and percentages among the right and left sides did not considerably differ. The number of impacted third molars in mandibular arches was higher than that in maxillary arches. Impactions in Position C were usually in the maxillary arch (116, 11.47%), whereas those in Position A were common in the mandible. Vertical and mesioangular impacted angulations were frequent in the mandibular arch (162, 22.0% and 118, 11.7%). Cases of distolingual impaction were high in the maxillary arch (96, 9.6%). Class II impacted teeth in relation to the ramus were the highest in the right (259, 25.6%), and left (239, 23.62%), followed by Class I impactions. Conclusion: The prevalence of impacted third molars was slightly higher in the Jazan region than in other regions in Saudi Arabia.

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BACKGROUND: Garre’s osteomyelitis is a rare type of chronic osteomyelitis that mainly affects children and young adults. This disease is commonly associated with an odontogenic infection resulting from dental caries. CASE REPORTS: This article describes two case reports of young boys with Garre’s osteomyelitis of mandible caused by odontogenic infection. RESULTS: The cases were managed by extraction followed by antibiotics and the healing was achieved uneventfully.

IntroductionThe palate, which plays an important role in oral cavity function, including the mastication and swallowing of food, obviously differs structurally with feeding habits. Nevertheless, the palate is considered the most common location of both benign and malignant minor salivary gland tumors. Soluble N‐ethylmaleimide‐sensitive fusion protein attachment protein receptor (SNARE) proteins are important in the control of tumorigenesis through the regulation of multiple signaling and transportation pathways. However, the developmental distribution of SNARE proteins on the palatal structures has been scarcely reported. Therefore, this study aimed to investigate SNARE proteins, syntaxin‐1, synaptosomal‐associated protein of 25 kDa (SNAP‐25) during the development of rat palates.Materials and MethodsImmunohistochemistry for protein gene product 9.5 (PGP 9.5), a pan‐neuronal marker, syntaxin‐1 and SNAP‐25 was performed on frozen sections of rat palatal tissues at different stages.ResultsPGP 9.5 immunoreactive fibers (IRF) were present in developing palate. They were observed along the palatal sub‐epithelial layer and the underlying connective tissues in association with developing acini, ducts, blood vessels. Nerve fibers containing syntaxin‐1 and SNAP‐25 showed similar distribution to PGP 9.5 and thick bundles of nerve fibers were observed with smooth muscles and varicoses. With maturation after postnatal day 7 (PN7), thin nerve fibers containing PGP 9.5 and SNAP‐25, but less syntaxin‐1, were detected penetrating into the epithelium, reaching beneath the cornified layer. They ramified out from subepithelial thick bundles into connective tissues until encircling the secretory units observed (PN21). In adults, the number of syntaxin‐1‐IRF was low in comparison with SNAP‐25 and PGP 5 fibers.ConclusionThe findings indicated the importance of SNARE proteins during the maturation of the palatal tissues.Support or Funding InformationNoneThis abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.