Background: The incidence of counterproductive behaviors among nurses in the workplace is another drastic phenomenon that is high among nurses who experience organizational cynicism feelings.Purpose : to identify the correlation between organizational cynicism and counterproductive work behaviors among nurses. Methods: This is a descriptive correlational study. The stratified random sampling technique used in this study . A total of 550 nurses were recruited from one University Hospital and one private hospital in Egypt. Data were collected using two self-administered questionnaires namely: Organizational cynicism scale (OCS): It is five point Likert scale used to measure organizational cynicism.It consists of three dimensions containing ( 14) items as the following; cognitive cynicism (5 items), affective cynicism (5 items), and behavioral cynicism (4 items). Responses ranged from 1 (completely disagree) to 5 (completely agree), and the mean score ranges from 1 to 5. Higher scores indicate higher levels of cynicism. Counterproductive Behaviors Scale (CBS):It is used to measure the incidence of counterproductive behaviors in workplace. It includes 23 items classified into five categories of counterproductive behaviors as the following; abuses against others (9 items), interference at work (3 items), sabotage (3 items), thefts (4 items), and avoiding work (4items). It is a 5 point Likert scale in which responses ranged from 1 (never) to 5 (every day). Results: The mean percentage score of organizational cynicism and counterproductive work behaviors were 90.18 ± 3.57, and 79.03 ± 1.99, respectively. Multivariate regression model revealed that organizational cynicism accounted for 40.2% of the variances in the incidence of counterproductive work behaviors. Conclusion: organizational cynicism is a significant antecedent for the incidence of counterproductive work behaviors among nurses. Implications to Nursing Management: Different strategies such as career development and advancement; considering nurses career goals and objectives; keep promises toward nurses; putting sound reward and punishment system; and make sure that policies, and goals, and practices are in alignment are helpful to prevent organizational cynicism and eradicate counterproductive work behaviors.