Background normal sexual activity is an important issue in the quality of life for both males and females. Several diseases were associated with erectile dysfunction, unfortunately, data about erectile dysfunction in cirrhotic patients was scanty. This study was conducted to determine the prevalence and risk factors of erectile dysfunction in patients with liver cirrhosis. Method: a cross-sectional study was conducted on 200 patients with liver cirrhosis they were divided into three groups according to Child score and erectile dysfunction was studied by (IIEF-5) Questionnaire and penile Doppler. Results the prevalence of erectile dysfunction in the cirrhotic patient was 80%. the erectile dysfunction worsens with the worsening of the liver condition (Child C), also 20% of the cirrhotic patients had penile venous leakage which became 28.6% in advance liver cirrhosis (Child C). Multivariate logistic regression showed that advancing in age, Albumin less than 2.8 g/dl, INR 1.7-2.2, Hb>16 g/dl and Child C were predictors of erectile dysfunction in cirrhotic patients. Conclusion Erectile dysfunction was found in 80% of cirrhotic patients. It was more frequently observed in cirrhotic patients having an advanced disease (child C). Patients reporting ED had elevated INR, serum bilirubin, suppressed serum albumin, and elevated level of hemoglobin.