Background: Obesity is considered a major risk factor for breast cancer. High-intensity interval training (HIIT) is a time-efficient exercise that significantly advances cardiorespiratory fitness in healthy subjects. Purpose:This study aimed to evaluate the effects of HIIT on cardiorespiratory fitness and body composition in survivors of breast cancer who are overweight and obese. Methods: Sixty overweight and obese female breast cancer survivors, aged 40 to 60 years, 6 months after completing therapies were included in this study. The patients were randomly allocated to 2 groups: the HIIT group (n = 30; administered HIIT program 3 sessions per week for 8 successive weeks) and the control group (n = 30; received usual care measures). Cardiorespiratory fitness, measured using maximal oxygen uptake ( VO 2peak ), and body composition were evaluated in patients of both groups at baseline and after the intervention period. Results: VO 2peak increased significantly by 3.77 mL.kg −1 .min −1 between pre-and posttreatment (P < .05) in the HIIT group. Body mass indexes in both groups were similar (P > .05). Women in the HIIT group showed significant fat mass changes, fat mass percentage, and lean body mass (P < .05). Conclusion: This study shows that HIIT effectively improves cardiorespiratory fitness and body composition in breast cancer survivors.

Objectives: This study aims to compare the effect of aquatic-based exercises (AQBEs) and land-based exercises (LBEs) on muscle strength, fatigue and quality of life (QoL), and skin disease activity in children with juvenile dermatomyositis (JDM). Patients and methods: The design of the study was an assessor-blinded, controlled 2x2 crossover trial. Fourteen children (4 boys, 10 girls; mean age 11.7±2.2 years; range, 10 to 16 years) were evaluated. AQBEs and LBEs were applied through two treatment sequences as half of the children received AQBEs first while the second half received LBEs first. Isometric muscle strength, fatigue level and QoL (Pediatric Quality of Life Inventory Multidimensional Fatigue Scale [PedsQL-MFS]), and skin disease activity score (DASskin) were measured at four occasions for each treatment sequence. Results: The AQBEs had significant superiority over LBEs with improved hip flexors' strength (p=0.007) and hip abductors' strength (p=0.001), while both types of treatment had the same effect in increasing strength of shoulder flexors and abductors (p<0.05). AQBEs improved PedsQL-MFS, and DASskin significantly more than LBEs (p<0.001). For all outcome measures, there was no significant difference in the treatment sequence the children received first. Conclusion: Supervised AQBEs are more effective in improving muscle strength, fatigue and QoL, and skin disease activity than LBEs in children with JDM. Furthermore, the treatment sequence had no significant effect on measured variables.

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