Abstract-The biodiversity of some Gastropods taxa were studied in three selected stations in Euphrates River middle of Iraq (Musayb; Saddat Al-hindya and Hindya city) from October 2011 to September 2012.Some Physico-chemical parameters( air &water temperature; pH; TDS; TSS; DO;BOD5; Total harhness) of water in this stations were estimated which have been calculated some biodiversity indices of the of Gastropods species in the study area. Five species of gastropods were recorded, and their density was varied significantly (p<0.01, p<0.05) among stations and months of study, so they showed positive and negative Correlations with physico-chemical parameters of the study area.