A 41 year old nondiabetic, non hypertensive male was admitted in AHD through neurosurgery OPD with the complaints of left eye watering and left sided weakness for 1 month. MRI examination revealed a mass / lesion in the left prepontine cistern, left CP angle with extension to left middle cranial fossa which was histologically found to be chondroma, an extremely rare tumour in the above mentioned location.

We immunohistochcmically and morphometrically examined the expression of gap junction protein connexin (Cx) in normal and crushinjured rat sciatic nerves using confocal laser scanning microscopy. Cx26 was localized in the perineurium and Cx43 was present in the perineurium and the cpineurium, whereas Cx32 was confined to the paranodal regions of the nodes of Ranvier. Double labeling for connexins and laminin revealed that Cx43 was localized in multiple layers of the perineurium, whereas Cx26 was confined to the innermost layer. Double labeling for connexins and a tight junction protein, occludin, showed that occludin frequently coexisted with Cx43, but existed separately from Cx26 in the perineurium. After crush injury, the pattern of normal Cx32 expression was initially lost but recovered, whereas Cx43 rapidly appeared in the cndoncurium and its expression was subsequently attenuated. Although crush injury produced no apparent alteration in Cx43 and occludin in the perineurium, a rapid increase and a subsequent decrease in the frequency of Cx26-positive spots during nerve regeneration were shown by morphometric analysis. These results indicate that Cx26, Cx32, and Cx43 are expressed differently in various types of cells in peripheral nerves and that their expressions are differentially regulated after injury. The expression of connexins and occludin in the perineurium suggests that perineurial cells are not uniform in type, and that the regulation of gap junctions and tight junctions is closely related in the perineurium. P-II-41 Radicicol has a potent neurotrophic effect on cultured sensory and sympathetic neurons from chick embryo.

Intranodal palisaded myofibroblastoma is a rare benign soft tissue tumor almost always arising from inguinal lymphnodes. It usually present as a painless, slow growing inguinal mass. We report herein a case of an intranodal palisaded myofibroblastoma occurring in a 43-year-old man along with its salient clinicopathologic features and differential diagnosis. Pulse volumel.11 January-December 2018-2019 p.19-21

Two baby's, one was 6 months old and another was 2 months old presented with a rapidly progressing melanotic neuroectodermal tumor of infancy (MNTI) in the maxilla. The tumor extended from the midline to the retromolar area of the left maxilla. It was confirmed as a melanotic neuroectodermal tumor through, radiology, cytology and histopathological examinations. The encapsulated tumor was excised .No recurrence was seen in the initial follow up nearly one year.

A 19-year-old female presented with backache and left hypochondralgia on and off for one year. Complete blood counts, urinalysis and culture were negative. Ultrasonogram revealed normal kidney and urinary bladder along with a lobulated solid mass at left adrenal region with focal peripheral calcification. Based on the findings, CT scan was advised. CT scan without contrast showed a mass in left adrenal region of approx 3.3x3.2x2.6 cm with punctuate calcification in the wall as well as within the mass. The mass was well encapsulated with predominant fat attenuation interspersed with septae. The left adrenal was not separately identified, hence a presumptive diagnosis of adrenal myelolipoma was considered. The patient underwent left adrenalectomy and the specimen was sent for histopathological examination. Histopathology showed a mass adherent to normal adrenal showing several well differentiated ectodermal structures (tooth, hair follicles, sweat and sebaceous glands etc) consistent with a mature teratoma. The patient recovered uneventfully and is doing well at present. DOI: http://dx.doi.org/10.3329/pulse.v5i1.20192 Pulse Vol.5 January 2011 p.54-56