Introduction: Measures of carotid artery flow or inferior vena cava diameter were recently shown to predict fluid responsiveness. Both are relatively superficial large vessels which can provide straightforward ultrasound evaluation & high-qualityimages.Methods: Our study is a prospective observational study on 30 mechanically ventilated septic shock patients in ICUto assess the fluid responsivenessby measuring carotid Doppler peak velocity&respiratory variation in inferior vena cava diameter against the increase in the cardiac index by echocardiographic calculations as a reference. All patients were given a fluid bolus 7 ml/ Kg crystalloid solution within 30 minutes, static and dynamic indices which include CVP, MAP, pulse pressure, difference between diameter of IVC during inspiration and expiration (ΔIVC- d) & carotid Doppler peak velocity in a single respiratory cycle (ΔCDPV) were measured before (T0) & after (T1). Vasoactive drugs infusion rate and ventilation settings did not changed during follow up. Patients were categorized either fluid responders “R” or non-responders “NR” according to an increase in cardiac output “CO” (increase in CO > 15 %.Results: Comparing responders & Non responders group we found a significant difference in Cardiac output measures,MAP & Δ CDPV pre & post fluid boluses as (5.26±4.42 L/min Vs. 10.62±5.73 L/min, 69.48±9.70 mmHg Vs. 84.90±10.36 mmHg&24.43±11.87%Vs33.22±11.00%) respectively with P-value (0.007, 0.05&0.01) respectively, on the other side , ΔD-IVC & Δ CVP pre & post fluid boluses didn’t show any statistical difference as (11.91±9.41 % Vs. 13.51±9.56 %, 5.86±5.22 cmH2O Vs 7.22±4.82 cmH2O) with P-value (0.87&0.68)respectively.Δ CDPV increase in response to increased intravascular volume in R group showed sensitivity 81%, specificity 66.7%. APACHE II, SOFA day 0,5 didn’t showed any difference between the R & NR group (16.05±3.23 Vs 18.44±3.81, 11.48±2.82Vs12.11±2.80& 12.95±3.68Vs12.56±3.97) respectively with P-value (0.164,  0.625 & 0.79) respectively. Conclusion: ΔCDPV was a more precise & even easier assessment tool with better sensitivity and specificity for evaluation of fluid responsiveness than the ΔD-IVC in patients with septic shock upon mechanicalventilation. Also, ΔCDPV has a high correlation with SVI increasing parameters assessed by echocardiography after fluid boluses. On the other hand and in comparison, CVP showed low accuracy in predicting fluid responsiveness.  

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ObjectiveThe Burch procedure remains an effective and durable procedure; however, it can be associated with many complications, the most important of which is voiding difficulties. To avoid overcorrection or undercorrection, placement of the sutures can be guided by a cystoscope to ensure equal placement and tension on both sides of the bladder neck. Patients and methodsIn all, 130 female patients with genuine urinary stress incontinence proved by urodynamic studies were enrolled in the study. They were operated upon by a Burch colposuspension guided by cystoscopic vision to the bladder neck during placement and tension of the sutures on both sides of the bladder neck. Results All patients were followed up for 6 months postoperatively: 122 of them for 12 months and the remaining eight for 24 months. All cases showed a negative stress test, and none of them suffered from urinary retention. Thirty-five cases (26.9%) who suffered urinary tract infection were treated medically; 11 cases (8.4%) reported urgency and were treated medically. ConclusionCystoscopy during Burch colposuspension could be helpful to guide the placement and adjustment of sutures. This additive simple procedure definitely improved the results of the procedure and decreased complications, especially urine retention and voiding difficulties.