This study was designed to investigate, model and optimise the influence of cooking treatments (untreated, boiling and steaming), ingredient-mix infusion temperature (30°C, 40°C and 50°C) and infusion duration (5, 10 and 15 min) on the quality indices of ingredient-mix based dried chicken product (chicken kilishi) produced from chicken breast. The quality indices (proximate composition and mineral contents) of the produced chicken kilishi were determined and analysed statistically using a hybrid Taguchi-Response Surface Methodology design. The production of chicken kilishi from untreated chicken breasts favours an increase in ash content (9.04%), crude protein content (50.28%) and zinc content (16.34 ppm). However, the chicken kilishi produced from the steaming treatment gives the highest fat content (14.02%), carbohydrate content (28.97%) and phosphorus content (12.07 ppm), while the kilishi subjected to the boiling treatment have increased iron content (18.24 ppm) but decreased moisture content (5.32%). The developed polynomial regression models for the quality indices were significant with R 2 and R 2 adj that ranges from 0.88 to 1.00, respectively. The optimum process conditions were attained when the chicken breasts were not treated and ingredient-mix infusion was conducted for 6 min at 41°C.