Water and cosmetics containing mercury can cause damage to the skin and body. There is a great need for in situ monitoring and removal of mercury ion concentrations with a highly selective, sensitive, accurate, rapid, and simple protocol in water and skin-whitening cosmetic products. In situ recognition is an easy and inexpensive approach for recognition and uptake of Hg 2+ ions in skin-lightening cosmetics and water. Our system is based on the fabrication of a sticklike structure of the newly developed metal−organic framework (MOF) via a solvothermal protocol. The rodlike structure of the Al-MOF has a tremendously high surface area which is a powering point that supported it as a microporous substrate for loading a Hg 2+ ion chromophore (bis(4-(dimethylamino)phenyl)methanethione). The thioketone derivative chromophore based on an Al-MOF microporous carrier allows visual monitoring of toxic mercury in a few seconds. The proposed chemosensors have a color change from yellow to a green color that is extremely noticeable by the naked eye. Our designated chemosensors sensitivity (0.8 ppb) toward mercury ions was found to be lower than the WHO permissible drinking water limits which made it a good choice for in situ pretests of drinking water. Moreover, superior adsorption characteristics of the fabricated thioketone Al-MOF (TAM) nanorods as adsorbent were achieved. A high adsorption capacity was observed (1110 mg/g) in solution for capturing of mercury ions. Our developed protocol is built on the use of a small amount of prepared optical chemosensors, about 20 mg, for all measurements and the potential for multiple uses after a simple regeneration process. Our results revealed that the designed TAM nanorods would be a promising means of visualizing mercury ions in water and cosmetics products.

Background: There are many laparoscopic techniques for pediatric congenital inguinal hernia repair. Needlescopic surgery was introduced recently in pediatric patients aiming at getting excellent cosmetic outcomes. Purpose:The aim of this study was to describe a novel technique for needlescopic inguinal hernia repair in children.Patients and Methods: Needlescopic division of the hernial sac was carried out on 369 children in 6 pediatric tertiary centers during the period from August 2016 to May 2019. All hernias were repaired by a novel needlescopic procedure that replicates all the steps of the open herniotomy.Results: A total of 369 patients with 410 hernias were included in this study. They were 232 (62.9%) males and 137 (37.1%) females, with a mean age of 3.58 ± 1.26 (range = 2 to 8 y) and mean internal inguinal ring diameter was 13.65 ± 3.85 mm (range = 8 to 20 mm). The mean operative time was 23.36 ± 4.67 minutes for bilateral and 14.28 ± 2.98 minutes for unilateral cases. All cases were completed without conversion to conventional laparoscopy. All cases were followed up for a mean of 19.6 ± 3.2 months. None of our patients developed recurrence or testicular atrophy and the scars were nearly invisible 3 months postoperatively.Conclusions: Needlescopic pediatric inguinal hernia repair using disconnection of the hernia sac at internal inguinal ring with pursestring suture closure of peritoneum is feasible and safe with no recurrence and with outstanding cosmetic results.

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Senna-based laxatives are effective treatment for overflow retentive stool incontinence and their doses can be adjusted initially depending on the analysis of the radiological data.