Aims: This study aims to determine the antioxidant enzyme EC-SOD polymorphisms in Egyptian patients with type 2 diabetes mellitus with and without retinopathy, and its association with other biochemical changes to assess whether decreased SOD activity is associated with the development of diabetic complications.

Background: Management of facial skin cancer and its complications is important research topics needing continuous update to improve the outcome. Objective:The study is to share our findings with surgeons and healthcare providers.The authors provide their efforts by pooling data from multiple institutions; as reporting surgical outcomes is significantly lacking and much needed in the Middle East and North Africa region in order to meaningfully improve quality of care. This study proposes an algorithm for management that could aid a surgical decision-making for reconstruction of defects after excision of facial skin cancer. Methods:Retrograde simple descriptive analysis study is conducted for multicenter data about management of facial skin cancer and its cosmetic outcome. The analysis involves 159 male patients and 95 females.Results: Nonmelanoma skin cancer was reported in 250 (98.4%) of 254 cases.Reconstructive procedures were complicated in 16 cases (~6.3% of the study). Skin cancer recurrence in head and neck has happened in five cases (~1.9% of the study).Flaps used survived without major complications; however, V-Y advancement flaps showed the best aesthetic outcome. Conclusion:This study reports data in order to meaningfully improve the quality of care. Disease incidence, reconstructive complications, recurrences, and aesthetic outcome of facial skin cancer are included in the study. Based on the data pooling, the study proposes a simple treatment algorithm that could aid in surgical decisionmaking. V-Y advancement flaps showed the best aesthetic outcome. K E Y W O R D Saesthetic, algorithm, face, multicenters, skin cancer | INTRODUC TI ONSkin cancer is classified into melanoma and nonmelanoma types. 1,2 Incidence of each type varies according to a genetic, predisposing, 3 ethnic, or geographic factor. 4 In management of facial, scalp, and neck skin cancer, surgery always has a basic contribution. 5 Surgeons and dermatologists have many choices for the closure of the defects after excision, according to each lesion; site and size, patient age skin elasticity, in addition to individual experience and understanding of facial proportion. 6,7

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Background:The fingertip is the portion of the digit distal to the insertion of the flexor and extensor tendons on the distal phalanx. The volar surface of the fingertips contains grooves and ridges, uniquely patterned for each individual, termed fingerprints. The digital arteries and nerves arborize or trifurcate near the distal interphalangeal joint. Aim of the Work:Evaluation of the outcome of sensate and non-sensate tissues for fingertip reconstruction. Patients and Methods:This study attempts to show the benefits of using different modalities for fingertip reconstruction in cases that presented in El Hussein and El Haram hospitals. Thirty-five cases of fingertip amputation were examined and managed using different techniques. In addition of managing these cases, we followed these cases over a 6 months period of time after first presentation and intervention to assess the outcome and any possible complications. Results:In this study, according to the Allen's classification the majority (34.2%) of cases showed amputation level class II. Only 5 cases (14.2%) did not have bone exposed. The middle finger was the most injured in our study (34%). Seven (20%) cases showed postoperative infection. Eighteen (51.4%) cases got involved in the physical treatment/ occupational therapy. Ten (28%) cases had numbness over the injured finger. Only Eighteen (51.4%) cases completely survived. Conclusion:Conservative wound management with dressings and a protective splint allows patients to avoid immobilization and donor site morbidity.