Background: Multidetector computed tomographic (MDCT) angiography has become a key imaging investigation for assessment of the renal vasculature challenging conventional angiography. Objective: To assess the diagnostic performance and accuracy of multi-detector computed tomography angiography in evaluation of renal vascular abnormalities. Subjects and Methods: Prospective study included 95 patients (60 males and 35 females) evaluated by MDCT renal аngiоgrаphy, divided into four groups .First group are renal donors prepared for renal transplant, Second group are patients with history of suspected renal trauma or post percutaneous nephrolithetomy hematuria ,Third group are patients suspected for renovascular hypertension . Fourth group are patients with renal masses assessed for preoperative angio-embolization & surgical guidance. MDCTA findings were correlated with conventional angiography or operative findings. Results: MCT angiography results show no significant statistical deference compared with intraoperative findings in first group, as well as compared with conventional angiography regards detection of pseudoaneurysmas in traumatic & post PCNL patients (P value > 0.05) in second group. In patients with suspected renovascular hypertension there was significant difference between renal artery Doppler findings & MDCT angiography as well as conventional angiography (P value <0.05). MDCT Angiography has AUC of 0.973, Sensitivity 93.3% and Specificity 90%. Conclusion: We can conclude that, MDCT Renal angiography is an excellent imaging investigation because it is a fast and non-invasive tool that provides detailed evaluation of normal renal vascular anatomy, variants &abnormalities .

Aim: To demonstrate the role of 18F-FDG PET/CT for detection of post-thyroidectomy recurrence in differentiated cancer thyroid patients with negative radio-isotope iodine scan, yet showing elevated serum thyroglobulin level. Procedure: This is a prospective study which included 20 patients who had previous history of differentiated cancer thyroid. All patients after history taking and revising the medical sheet underwent Serum Thyroglobulin level Estimation & entire body scan I-131 (WBS) examination and then 18F-FDG PET/CT study. The findings of PET/CT imaging were compared with histopathology results or clinical follow-up results as a gold standard. Results: FDG PET/CT based analysis showed that 19 true positives and 1 was true negative as confirmed by the gold standard (Histopathology and clinical follow-up). 13 patients had either local recurrence or lymph node metastases without distant metastatic disease, 6 patients had different distant metastasis. 18F-FDG PET/CT based analysis showed that 19 true positives and 1 was true negative as confirmed by the gold standard (Histopathology and clinical follow-up). The sensitivity and accuracy of PET/CT (95%) were significantly better than those of the CT alone (84.2% and 80%, respectively) [P=0.03]. Conclusion: Combination between positron emission tomography (PET) and computed tomography (CT) allow anatomic, functional & molecular information. 18F-FDG PET/CT provided a critical role in assessment and management of patients with suspected differentiated thyroid recurrence, presenting with high serum thyroglobulin level and negative radio-isotope scan. The 18F-FDG PET/CT enhance diagnostic accuracy through giving exact anatomical localization of recurrent and/or metastatic tumor foci.

Background Thyroid cancer considered the 6th common cancer in female and represents approximately 1% of all cancers. Thyroid cancer is generally characterized by good prognosis, long term survival and low aggressiveness. Its prognosis is related to tumor dimensions, extra capsular extensions, the age at diagnosis and distant metastases sites. Combination between positron emission tomography and computed tomography allow anatomic, functional & molecular information. Aim To demonstrate Fluorine 18 fluorodeoxyglucose positron emission tomography)/computed tomography role for evaluation of post-thyroidectomy recurrence either local or distant metastatic lesions in differentiated cancer thyroid patients with negative radio-isotope iodine scan, yet showing elevated serum thyroglobulin level. Procedure A prospective study included twenty patients with previous history of differentiated thyroid cancer. All patients after history taking and revising the medical sheet underwent Serum Thyroglobulin level & I-131 whole body scan examinations and then Fluorine 18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography study. The findings of Positron Emission Tomography/Computed Tomography imaging compared with results of histopathology or follow-up clinical results as a gold standard. Results Fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography based analysis showed that nineteen true positives and one was true negative as confirmed by the gold standard (Histopathology and clinical follow-up). Thirteen patients had either local recurrence or lymph node metastases without distant metastatic disease, six patients had different distant metastasis. Fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography based analysis showed that nineteen true positives and one was true negative as confirmed by the gold standard (histopathology and clinical follow-up). The accuracy and sensitivity of Fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography (95%) were significantly better than those of the Computed Tomography alone (84.2% and 80%, respectively). Conclusions Fluorine 18 Fluorodeoxyglucose positron emission tomography/computed tomography provided a critical role in assessment and management of patients with suspected differentiated thyroid recurrence, presenting with high serum thyroglobulin level and negative radio-isotope iodine scan. It enhances diagnostic accuracy through giving exact anatomical localization of recurrent and/or metastatic tumor foci.