ABSTRAGT: Seventy‐five women suffering from acne vulgaris classified into three groups according to the grade of the disease. Anti‐androgenic tablets cyproterone acetate (CPA), were given in three cycles. The total numher of patients whose condition improved was 52% after the first cycle, 55% after the second cycle, and 81.3% after the third cycle. No serious side effects were encountered. CPA is a suitable therapeutic modility for AV in women who use contraceptives.