No abstract

Sarcoidosis is a multisystem, inflammatory disorder characterized by the presence of noncaseating epithelioid granulomas. Sarcoidosis can involve the genitourinary system by affecting the kidney and genitals. Most characteristic genital lesions proceed to granuloma and can comprise the epididymis, testis, and vas deferens. Few case reports have been published on this rare entity. We report a case in which a man presented with bilateral epididymal sarcoidosis and severe oligospermia. Corticosteroid treatment, which was applied in gradually decreasing doses for 6 months, dissolved the testicular granuloma. Consequently, semen analysis demonstrated a significant increase in the sperm count to within normal limits.

ARTICLE INFO ______________________________________________________________ ______________________Purpose: Aim of this study is to examine the effectiveness of dextranomer/hyaluronic acid copolymer and polyacrylate polyalcohol copolymer in endoscopic treatment of vesicoureteral reflux disease in adult patients with and without chronic renal failure. Materials and Methods: Thirty two patients (12 female, 20 male) with a total of 50 renal units were treated for vesicoureteral reflux. There were 26 (81%) chronic renal failure patients. The success of treatment was evaluated by voiding cystouretrography at 3rd and 12th months after subureteric injection. The persistence of reflux was considered as failure. Patients were divided into two groups according to injected material. Age, sex, grade of reflux and treatment results were recorded and evaluated.Results: Reflux was scored as grade 1 in seven (14%), grade 2 in 16 (32%), grade 3 in 21 (42%) and grade 4 in six (12%) renal units. There was not patient with grade 5 reflux. Fourteen renal units (28%) were treated with dextranomer/hyaluronic acid copolymer (group 1) and 36 renal units (72%) were treated with polyacrylate polyalcohol copolymer (group 2). The overall treatment success was achieved at 40 renal units (80%). The treatment was successful at 11 renal units (79%) in group 1 and 29 renal units (81%) in group 2 (p = 0.71). There was not statistically significant difference between two groups with patients with chronic renal failure in terms of treatment success (p = 1.00). Conclusions:The effectiveness of two bulking agents was similar in treatment of vesicoureteral reflux disease in adult patients and patients with chronic renal failure.

Metastatic malignant melanoma of the prostate is extremely rare in clinical practice, and only one case has been reported in the English literature in the past 30 years. We report a case of malignant melanoma that metastasized to the prostate and review the current literature. A 50-year-old man with a history of malignant melanoma metastasis to the left axilla, which was excised 3 years ago, presented with lower urinary tract symptoms and gross hematuria. He underwent cystoscopy and transurethral resection of the prostate. The pathological examination showed metastatic malignant melanoma of the prostate gland. The patient died 6 months after the transurethral resection.

Objective: The aim of this study was to examine the effects of the retropubic and perineal radical prostatectomy techniques on postoperative urinary continence. Material and methods:This study included patients who had undergone radical retropubic (RRP) (n=54) or radical perineal prostatectomies (RPP) (n=142) in our clinic between December 2006 and December 2010 with the indication of localized prostate cancer. Preoperative, and postoperative continence levels of the patients were evaluated on the day of catheter removal, and at 3., 6. or 12. months using University of California-Los Angeles (UCLA) prostate cancer index query forms completed by the patients themselves in outpatient clinics.Results: Mean ages of the perineal, and retropubic groups were 62.3 (48-77), and 62.5 (50-74) years, respectively. The absolute urinary control rates of the RPP patients on the first days, and the first, third, sixth, and twelfth months were 44.3, 63.6, 76.2, 79.5, and 86.1%, respectively. The same rates were 51.4, 75.7, 78.4, 89.2, and 91.9% for the RRP group, respectively. Conclusion:There was no significant difference between RRP groups as for the frequency of urinary incontinence.