The paper describes the analysis and assessment of non-profit sector development drivers in the Republic of Kazakhstan. The authors identify the most significant factors that influence the nonprofit sector on the basis of multifactor correlation and regression analysis. The scale of the non-profit sector is determined on the basis of two indicators: the number of non-profit sector institutions and Global Venture Alliance (GVA). The authors have estimated two analysis options. The first option assesses the effect of the economy on the number of institutions (inflation, government expenditures on the social sphere, actual final consumption) and the effect of the population (employment, income, number of socially vulnerable groups). The most significant factors were income indicators, their correlation with the minimum subsistence level and the number of socially vulnerable groups. The second option considered GVA as a resulting indicator and studied the dependence of the sector's economic results on its potential, and the sector's state support on the population's standard of living and the number of socially vulnerable groups. The influence of the state social contract does not have a positive effect on the sector's GVA volume, which indicates the problem in its priorities and distribution mechanisms. The authors proposed a transition to the consumer subsidy model and infrastructure support for social entrepreneurship development as one of the priority directions of non-profit sector transformation.