Nowadays, hospital information systems (HIS) provide real-time data and information in order to guide public health organizations especially in decision-making. The hospital information systems are integrated information systems designed to manage the administrative, financial and clinical tasks or aspects of a hospital. It plays an important role in planning, initiating, organizing and controlling the operations of the hospital, and a crucial role in providing quality healthcare services. The aims of this paper are to explore and provide a better understanding of data security aspects in hospital information systems, and add more body of knowledge in information systems (IS) field in the healthcare industry. The views of previous researches are presented and discussed, and new area of interest to the IS and HIS community then are proposed.