This article is investigating modernity and ethnic-demographic development in the southern region of Kyrgyzstan. Socioeconomic and political reforms, market relations, social and economic instability in the country in early years of sovereignty decisively influenced by the dynamics and character of population. That is why a deep and comprehensive study of the Republics ethnic-demographic process is relevant nowadays. In this work, based on statistical data, the general description of population dynamics, its ethnic composition, and migration processes in a current ethnic-demographic situation was described.