We report a rare case of bilateral Idiopathic Retinitis, Vasculitis, Aneurysms, and Neuroretinitis (IRVAN) with occlusive vasculitis.A 28-year-old female presented with sudden decreased vision in her left eye for three days. Visual acuity in the right eye was 6/6, whereas it was 6/9 in the left eye. The anterior segment was examined and found to be normal. A fundus examination of the right eye showed an arteriolar aneurysm on the optic disc, vascular sheathing, and generalized retinal pigment epithelial atrophy. The left eye was in worse condition, with a swollen optic disc, disc hemorrhage, multiple arteriolar aneurysms, hard exudates at the peripapillary and macular region, peripheral vasculitis, neovascularization, and vitreous hemorrhage. Optical coherence tomography revealed mild cystoid macula edema (CME) in both eyes. Fluorescein angiography of both eyes demonstrated arteriolar aneurysms, vascular leakage, and peripheral ischemia. There was additional leakage from new vessels and masking secondary to vitreous hemorrhage in the left eye. The results of the systemic evaluation and extensive laboratory testing were negative. She had bilateral retinal photocoagulation and was administered oral prednisolone later with slow tapering due to increasing CME. Her eye condition did not worsen, and she maintained good vision in both eyes.IRVAN, even though rare, should be suspected in patients with occlusive vasculitis, arteriolar aneurysm, and macula exudation. Since the nature of the disease is more aggressive than other ischemic retinopathies, early detection, intervention, and close follow-up are crucial to prevent rapid visual loss.
Introduction: Cataract is the main cause of preventable blindness worldwide and as such, it is important to identify these patients early before complications develop. Cataracts may progress to become intumescent (phacomorphic) or hypermature (phacolytic). This can lead to lens-induced glaucoma, which may subsequently cause permanent optic nerve damage.Objective: To report on lens-induced glaucoma (LIG) of cataract cases treated in Hospital Sultanah Nur Zahirah, Kuala Terengganu (HSNZKT), Malaysia.Method: National Eye Database (Malaysia) data from 2011 till 2017 were collected and analysed.Results: A total of 81 (1.08%) cases of lens-induced glaucoma were calculated from 7468 cataract cases treated during the seven years of the study period. The number of cases showed an increasing trend with 0.78% in 2011 to 1.26% in 2017. Most of the patients were in the age group of 70-79 years (44.30%), followed by 60-69 years (34.18%), 50-59 years (11.39%), 80-89 years (7.59%), 40-49 years, and 90-99 years (1.27%). Most of the cases are female (57%). The majority of them (79.75%) underwent cataract operation for the first eye.Conclusion: Overall, this study was able to highlight the significant association between the incidence of LIG and increasing age as well as surgery series (either first or second eye). Therefore, more outreach programs should be conducted in the future to enable younger elderly patients from all areas to receive treatment. More online education and talk series can be organized to increase the community's awareness and acceptance of cataract operations.
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