Introduction Surgery for Hashimoto thyroiditis (HT) can be difficult due to dense inflammatory process surrounding the gland and postoperatively patient can develop hypocalcaemia, recurrent laryngeal nerve injury, haematoma and infection. Purpose of this study was to compare the rate of post-operative complications in HT with that in benign goitres. Materials and Methods Data of the patients, who underwent thyroidectomy for benign goitres between January 2013 and December 2017, were reviewed retrospectively. Patients were divided in to two groups. Group A included patients confirmed to have Hashimoto thyroiditis (n=148) and Group B included patients who underwent thyroidectomy for other benign thyroid disorders (n=430). Results A total of 578 patients who underwent thyroidectomy for benign thyroid diseases were included in the present retrospective study. Group A consisted of 148 patients who had HT. Group B consisted of 430 patients who had other benign thyroid diseases. The data was analysed using SPSS 23 and p-value < 0.05 was considered as statistically significant. Patients undergoing thyroidectomy in HT had significantly higher post-operative complication rate (p<0.005). Of the 148 patients with HT, 31.6% (77) had hypocalcaemia while 68.4% (167) with benign goitres had hypocalcaemia. In addition, 51.8% of the patients in the HT group were later diagnosed with malignancy; there were no malignancies present in the group B. Conclusion Though patients with HT suffer higher rate of complications after thyroidectomy when compared to benign goitres, careful pre-operative planning and risk counselling of patients with improved surgical techniques helps to minimize postoperative morbidity.
Introduction: Hashimoto’s thyroiditis is the most common inflammatory disease of thyroid and papillary carcinoma of thyroid is an epithelial malignancy and is the most frequent thyroid neoplasm. The association between Hashimoto’s thyroiditis and papillary carcinoma of thyroid has been debatable due to conflicting evidence. Aim: To know the socio-demographic determinants of Hashimoto’s thyroiditis and to find out the association between Hashimoto’s thyroiditis and papillary carcinoma of thyroid. Materials and Methods: In this retrospective study, clinical and histopathological data of 720 patients who underwent thyroidectomy were studied at Father Muller Medical College, Mangalore, Karnataka, India. Clinical case records, from October 2013 till September 2018, and histopathological reports were collected. The results were expressed in percentages, proportions and means with standard deviation. Chi-square test was used to find out the association of age group, sex and histopathologic findings with Hashimoto’s thyroiditis. The data was analysed using SPSS version 23.0 and p-value <0.05 was considered as statistically significant. Results: Mean age of the study participants with and without Hashimoto’s thyroiditis was 45.94 (±10.60) years and 45.88 (±12.88) years respectively. Out of 720 study participants, 623 (86.5%) were females and 97 (13.5%) males. The most common indication for thyroidectomy was benign thyroid disorders followed by papillary carcinoma of thyroid. Mean age of Hashimoto’s thyroiditis was seen significantly higher in females compared to males (χ2 =12.214, p<0.001) and odds of females having Hashimoto’s thyroiditis was 3.76 times that of males and this was found to be statistically significant. Papillary carcinoma was seen in 157 cases out of 720 cases, and amongst them, 51 (32.5%) had Hashimoto’s thyroiditis. Papillary carcinoma was found to be associated with the presence of Hashimoto’s thyroiditis (χ2 =17.5, p <0.001). Conclusion: Female sex was the significant socio-demographic determinant of Hashimoto’s thyroiditis. Papillary carcinoma of thyroid was found to be associated with Hashimoto’s thyroiditis.
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