Purpose: This study aimed to compare the conventional eye patch with Occlu-tab—a binocular open-type amblyopia training device—and evaluate their effectiveness in amblyopia treatment. Methods: In this prospective, multi-center study, 40 patients between ages 3 to 12 years, diagnosed with anisometropic amblyopia (refraction difference of both eyes ≥ 2 D, best-corrected visual acuity [BCVA] of the amblyopic eye ≤ 0.1 [logMAR]) were treated with Occlu-tab or conventional eye patch for 1 h per day thrice a week. We compared the visual acuity of both groups before and after 6, 7, and 8 weeks of amblyopia treatment. One-way repeated-measures analysis of variance and Tukey’s test were used to compare the visual acuity of both groups pre- and post-treatment. Results: Both groups had significantly improved visual acuity at 6, 7, and 8 weeks compared to that before treatment (all P < 0.001). The improvement in BCVA of the Occlu-tab group (0.33 ± 0.25) was significantly greater than that of the eye patch group (0.16 ± 0.17) after 8 weeks of treatment ( P = 0.02). Conclusion: Amblyopia treatment using binocular open game training with Occlu-tab led to greater improvement in visual acuity than that with a conventional eye patch for the same treatment duration.

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The novel intronic mutation found in the proband confirmed the clinical diagnosis as a severe type of HI and has helped the family in providing precise genetic counseling for further prevention of the disease and carrier screening of other family members.

She is responsible for programs at the pre-college, undergraduate, and graduate levels to facilitate the recruitment, retention, and overall success of students from traditionally underrepresented groups in engineering and information and computer sciences. Dr. Artis has 18 years of experience working with education and outreach programs in engineering and over 35 publications in STEM education and outreach. Prior to joining UC Irvine, she was the Education and Outreach Director for the

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