Objective: In December 2019, the world experienced spread of severe acute respiratory syndrome- Coronavirus disease 2019 (COVID-19). Measures to contain spread included movement restrictions (Lockdown), quarantine for contacts, and institutional care for those infected. Fear of contracting the infection, mortality rates, experience of a lockdown, and economic concerns exposed people to great stress. On this background, the present study was conducted to assess psychological distress in these times. Methods: Consenting individuals comfortable to respond to an online survey were included as subjects. The study is cross-sectional in design; descriptive analysis and Chi-square tests were done. Socio demographic details were collected. Kessler 10 Psychological Distress Scale was administered to assess psychological well-being. Results Psychological distress was seen in 68% of the sample, ranging from mild-to-severe, across all age group, except in those below 18 years. Those aged 30–59 years experienced psychological distress before lockdown as well. Females experienced more distress than males, as well as those of the group with lower income. Conclusions: Responsibility of maintaining psychological well-being rests with each of us. Healthcare workers and mental health professionals need to identify and address psychological issues in the population during this period. Governmental organizations must take on the responsibility to educate the public through newspapers, television, and social media about the importance of maintaining positive psychological health and contribute to the same by honest journalism.