Background Chronic Obstructive Pulmonary Disease (COPD) impairs the function of the diaphragm by placing it at a mechanical disadvantage, shortening its operating length and changing the mechanical linkage between its various parts. This makes the diaphragm's contraction less effective in raising and expanding the lower rib cage, thereby increasing the work of breathing and reducing the functional capacity. Aim of the Study To compare the effects of diaphragmatic stretch and manual diaphragm release technique on diaphragmatic excursion in patients with COPD. Materials and Methods This randomised crossover trial included 20 clinically stable patients with mild and moderate COPD classified according to the GOLD criteria. The patients were allocated to group A or group B by block randomization done by primary investigator. The information about the technique was concealed in a sealed opaque envelope and revealed to the patients only after allocation of groups. After taking the demographic data and baseline values of the outcome measures (diaphragm mobility by ultrasonography performed by an experienced radiologist and chest expansion by inch tape performed by the therapist), group A subjects underwent the diaphragmatic stretch technique and the group B subjects underwent the manual diaphragm release technique. Both the interventions were performed in 2 sets of 10 deep breaths with 1-minute interval between the sets. The two outcome variables were recorded immediately after the intervention. A wash-out period of 3 hours was maintained to neutralize the effect of given intervention. Later the patients of group A and group B were crossed over to the other group. Results In the diaphragmatic stretch technique, there was a statistically significant improvement in the diaphragmatic excursion before and after the treatment. On the right side, p=0.00 and p=0.003 in the midclavicular line and midaxillary line. On the left side, p=0.004 and p=0.312 in the midclavicular and midaxillary line. In manual diaphragm release technique, there was a statistically significant improvement before and after the treatment. On the right side, p=0.000 and p=0.000 in the midclavicular line and midaxillary line. On the left side, p=0.002 and p=0.000 in the midclavicular line and midaxillary line. There was no statistically significant difference in diaphragmatic excursion in the comparison of the postintervention values of both techniques. Conclusion The diaphragmatic stretch technique and manual diaphragm release technique can be safely recommended for patients with clinically stable COPD to improve diaphragmatic excursion.
The root systems of mangroves, a tree species found in intertidal tropical and subtropical coastal zones, provide a natural barrier that dissipates wave energy effectively and reduces sediment erosion. In this work, we use a combination of experiments and numerical simulations to examine the wake and drag characteristics of porous arrays of cylinders, which serve as simplified models of mangrove root networks. Optimal arrangements of the arrays are obtained by coupling Navier-Stokes simulations with a multi-objective optimization algorithm, which seeks configurations that minimize wake enstrophy and maximize drag acting on the porous structure. These optimal configurations are investigated using Particle Image Velocimetry, and the internal and external flow around the porous arrays are analyzed using a combination of Proper Orthogonal Decomposition and Lagrangian particle tracking. Large variations in drag and enstrophy are observed by varying the relative positions of the cylinders, which indicates that the geometrical arrangement of porous arrays plays a prominent role in determining wake and drag characteristics. A sensitivity analysis suggests that enstrophy is more sensitive than drag to specific cylinder placement, and depends on distinctive flow patterns that develop in the interior due to interactions among individual cylinders. Arrays with higher drag are found to have higher average flow speeds in the wake and give rise to time-varying Lagrangian Coherent Structures, making them unfavorable for particle deposition and erosion. Overall, the results indicate that high-level metrics such as array porosity may not be sufficient on their own for predicting wake and drag characteristics.
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