Neurofibromatosis 1 is a rare inherited autosomal dominant syndrome. It comprises 90 % of neurofibromatosis cases. These patients may develop various types of tumours in early age, especially multiple neurofibromas with a high risk of developing malignant peripheral nerve sheath tumours. Other tumours can also develop like pheochromocytoma, optic nerve and brain stem gliomas, carcinoids and rarely gastrointestinal stromal tumours. A combination of pheochromocytoma and gastrointestinal stromal tumour is very rare. Only a few cases have been reported. Here, we are reporting a case of NF1 syndrome with a combination of pheochromocytoma and gastrointestinal stromal tumour with additional findings of multiple clear cell nodules and brown fat in the periadrenal connective tissue.
Pure BiFeO3(BFO) and 20% doped BFO with Holmium (Ho) and Neodymium (Nd) separately (Ho-BFO and Nd-BFO) samples are synthesized using solid state reaction method. Structural characterization is carried out using XRD and FTIR analysis. Further morphological study is performed to assist the structural analysis. In addition to these, thermal analyses such as tg-DTA comparisons are also presented here. These studies provide the understanding of impact of doping in modifying structure and related inherent properties of BFO multiferroics which are normally associated with their tuned electric and magnetic properties.
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