ABSTRAKStaphylococcus epidermidis merupakan salah satu bakteri penyebab penyakit kulit seperti jerawat. Getah jarak pagar (Jatropha curcas L.) merupakan bahan alami yang terdapat di batang tanaman yang memiliki efek sebagai antibakteri, karena mengandung senyawa aktif berupa flavonoid, alkaloid, tanin dan saponin. Tujuan penelitian ini adalah untuk mengetahui konsentrasi getah jarak pagar (Jatropha curcas L.) dalam menghambat pertumbuhan bakteri Staphylococcus epidermidis. Penelitian ini menggunakan rancangan acak lengkap (RAL) dan dianalisis dengan uji One Way ANOVA dan uji Duncan dengan 4 konsentrasi 25%, 50%, 75%, dan 100%, kontrol positif yaitu kloramfenikol dan kontrol negatif yaitu akuades steril. Hasil statistik diameter zona hambat adanya perbedaan yang signifikan (p0,05) pada setiap konsentrasi dilihat dari nilai diameter zona hambat. Konsentrasi getah jarak pagar (Jatropha curcas L.) yang mampu menghambat pertumbuhan bakteri Staphylococcus epidermidis terdapat pada konsentrasi 100% (11,58 mm) dibandingkan konsentrasi 75% (9,10 mm), konsentrasi 50% (8,60 mm), dan konsentrasi 25% (7,10 mm), sedangkan untuk kontrol positif (18,07 mm) dan kontrol negatif (0,00 mm). Hal ini dapat disimpulkan bahwa getah jarak pagar (Jatropha curcas L.) berpengaruh pada pertumbuhan bakteri Staphylococcus epidermidis. Kata Kunci : Getah Jarak Pagar (Jatropha curcas L.), Staphylococcus epidermidis, Antibakteri. ABSTRACTStaphylococcus epidermidis on of the bacteria that causes skin diseases such as acne. Jatropha sap (Jatropha curcas L.) is a natural ingredient found in plat stems which has an antibacterial effect because it contains active compounds in the from of flavonoids, alkaloids, tannins, and saponins. The purposes of this study was to determine the concentration of jatropha sap (Jatropha curcas L.) in inhibiting the growth of Staphylococcus epidermidis bacteria. This study used a completely randomized design and analyzed by One Way ANOVA test and Duncan test with 4 concentration of 25%, 50%, 75%, and 100%, positive control namely chloramphenicol and aquades as negative control. The statistical results of the inhibition zone diameter showed a significant difference (p0,05) at each concentration seen from the value of the inhibition zone diameter. The concentration of jatropha sap (Jatropha curcas L.) which can inhibit the growth of Staphylococcus epidermidis bacteria is found at a concentration of 100% (11,5 mm) compared to a concentration of 75% (9,1 mm), a concentration of 50% (8,6 mm), and a concentration of 25% (7,1 mm), positive control (18,0 mm) and negative control (0,0 mm). it can be concluded that the jatropha sap (Jatropha curcas L.) has an effect on the growth of Staphylococcus epidermidis bacteria. KeyWords : Jatropha sap (Jatropha curcas L.), Staphylococcus epidermidis, Antibacterial.
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